2019
A Case Study of Two Rodent-Borne Viruses: Not Always the Same Old Suspects
Childs J, Klein S, Glass G. A Case Study of Two Rodent-Borne Viruses: Not Always the Same Old Suspects. Frontiers In Ecology And Evolution 2019, 7: 35. DOI: 10.3389/fevo.2019.00035.Peer-Reviewed Original ResearchLCMV infectionRodent-Borne VirusesSolid organ recipientsPrevalence of infectionHuman diseasesWild rodent reservoirsSevere congenital diseaseSporadic sheddingAcute human diseaseOrgan recipientsChronic infectionWild rodent hostsRodent hostsSeoul virusFatal diseaseSEOVCongenital diseaseGolden hamstersInfectionPet rodentsLaboratory workersDiseaseMiceGenus HantavirusHundreds of cases
2001
Persistent infection in Neotoma fuscipes (Muridae: Sigmodontinae) with Ehrlichia phagocytophila sensu lato.
Castro M, Nicholson W, Kramer V, Childs J. Persistent infection in Neotoma fuscipes (Muridae: Sigmodontinae) with Ehrlichia phagocytophila sensu lato. American Journal Of Tropical Medicine And Hygiene 2001, 65: 261-7. PMID: 11693866, DOI: 10.4269/ajtmh.2001.65.261.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, BacterialArachnid VectorsBase SequenceBorrelia burgdorferiCaliforniaDisease ReservoirsDNA, BacterialEhrlichiaEhrlichiosisFemaleFluorescent Antibody Technique, IndirectHeat-Shock ProteinsHumansIxodesMaleMicePolymerase Chain ReactionRatsRodent DiseasesSeasonsSeroepidemiologic StudiesSigmodontinaeZoonosesConceptsPolymerase chain reaction testingGroESL heat shock operonPersistent infectionReaction testingRatsE. phagocytophilaLyme diseaseBorrelia burgdorferiMiceSeropositive animalsDusky-footed wood ratsPCRWood ratsSeroreversionSensu latoSeroconversionSeropositiveBiopsySerologySeroreactivityInfectionDiseaseBloodAdult Ixodes pacificus CooleySerum
1999
Population Dynamics of a Naturally Occurring Heterogeneous Mixture of Borrelia burgdorferiClones
Hofmeister E, Glass G, Childs J, Persing D. Population Dynamics of a Naturally Occurring Heterogeneous Mixture of Borrelia burgdorferiClones. Infection And Immunity 1999, 67: 5709-5716. PMID: 10531219, PMCID: PMC96945, DOI: 10.1128/iai.67.11.5709-5716.1999.Peer-Reviewed Original ResearchConceptsC3H/HeJ miceC.B-17 miceLarval Ixodes scapularis ticksMajority of miceB. burgdorferiInfected nymphal ticksIxodes scapularis ticksBurgdorferi antibodiesSecondary challengeHeJ micePrimary isolatesSequential isolatesC3H miceSequential infectionMiceMonoclonal antibodiesBorrelia burgdorferiC expressionScapularis ticksClonal dominanceUnique isolatesMacrorestriction analysisOspC proteinsClonal groupsEnzootic siteDusky-Footed Wood Rats (Neotoma fuscipes) as Reservoirs of Granulocytic Ehrlichiae (Rickettsiales: Ehrlichieae) in Northern California
Nicholson W, Castro M, Kramer V, Sumner J, Childs J. Dusky-Footed Wood Rats (Neotoma fuscipes) as Reservoirs of Granulocytic Ehrlichiae (Rickettsiales: Ehrlichieae) in Northern California. Journal Of Clinical Microbiology 1999, 37: 3323-3327. PMID: 10488199, PMCID: PMC85556, DOI: 10.1128/jcm.37.10.3323-3327.1999.Peer-Reviewed Original ResearchConceptsBlood samplesBlood specimensDusky-footed wood ratsConcurrent high prevalenceSeronegative blood samplesHuman granulocytic ehrlichiosisGroESL heat shock operonGranulocytic ehrlichiaePCR-positive animalsPCR positivityHigh prevalencePCR-positive ticksSeropositive specimensRat blood samplesRatsGranulocytic ehrlichiosisEhrlichial DNAPacificus adultsEhrlichia equiEhrlichial agentsMicePCR assaysAdultsWood ratsRodentsLongitudinal study of infection with Borrelia burgdorferi in a population of Peromyscus leucopus at a Lyme disease-enzootic site in Maryland.
Hofmeister E, Ellis B, Glass G, Childs J. Longitudinal study of infection with Borrelia burgdorferi in a population of Peromyscus leucopus at a Lyme disease-enzootic site in Maryland. American Journal Of Tropical Medicine And Hygiene 1999, 60: 598-609. PMID: 10348235, DOI: 10.4269/ajtmh.1999.60.598.Peer-Reviewed Original ResearchConceptsPolymerase chain reactionB. burgdorferiJuvenile miceCross-sectional sampleEar tissueBorrelia burgdorferi infectionIxodes scapularis ticksInfected miceSusceptible miceChronic infectionOverall prevalenceIncidence rateBurgdorferi infectionHigh riskLower riskInfectionMiceInfected ticksLongitudinal sampleBorrelia burgdorferiScapularis ticksChain reactionBurgdorferiLongitudinal studyIndirect transmissionHantavirus (Bunyaviridae) infections in rodents from Orange and San Diego counties, California.
Bennett S, Webb J, Madon M, Childs J, Ksiazek T, Torrez-Martinez N, Hjelle B. Hantavirus (Bunyaviridae) infections in rodents from Orange and San Diego counties, California. American Journal Of Tropical Medicine And Hygiene 1999, 60: 75-84. PMID: 9988327, DOI: 10.4269/ajtmh.1999.60.75.Peer-Reviewed Original ResearchConceptsHantavirus antibodiesHarvest miceReverse transcription-polymerase chain reactionTranscription-polymerase chain reactionDeer miceEl Moro Canyon virusBroad geographic rangeMale deer miceMajority of rodentsSNV antibodyAntibody-positive rodentsSan Diego CountyVirus antibodiesAntibody prevalenceHantavirus infectionSeropositive rodentsMicrohabitat selectionCactus mouseGeographic rangeFood plantsWestern blotHost distributionMiceCalifornia volesP. maniculatus
1998
ISOLATION OF BARTONELLA SPP. FROM EMBRYOS AND NEONATES OF NATURALLY INFECTED RODENTS
Kosoy M, Regnery R, Kosaya O, Jones D, Marston E, Childs J. ISOLATION OF BARTONELLA SPP. FROM EMBRYOS AND NEONATES OF NATURALLY INFECTED RODENTS. Journal Of Wildlife Diseases 1998, 34: 305-309. PMID: 9577777, DOI: 10.7589/0090-3558-34.2.305.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, NewbornAntibodies, BacterialBacteremiaBartonellaBartonella InfectionsCitrate (si)-SynthaseColony Count, MicrobialEmbryo, MammalianFemaleFetal DiseasesInfectious Disease Transmission, VerticalPeromyscusPhylogenyPlacentaPregnancyPregnancy Complications, InfectiousRodent DiseasesSigmodontinae
1995
Analysis of Borrelia burgdorferi Sequentially Isolated from Peromyscus leucopus Captured at a Lyme Disease Enzootic Site
Hofmeister E, Childs J. Analysis of Borrelia burgdorferi Sequentially Isolated from Peromyscus leucopus Captured at a Lyme Disease Enzootic Site. The Journal Of Infectious Diseases 1995, 172: 462-469. PMID: 7622890, DOI: 10.1093/infdis/172.2.462.Peer-Reviewed Original ResearchEAR BIOPSY LOCATION INFLUENCES DETECTION OF BORRELIA BURGDORFERI BY PCR, BUT NOT BY CULTURE IN NATURALLY INFECTED PEROMYSCUS LEUCOPUS
Hofmeister E, Childs J. EAR BIOPSY LOCATION INFLUENCES DETECTION OF BORRELIA BURGDORFERI BY PCR, BUT NOT BY CULTURE IN NATURALLY INFECTED PEROMYSCUS LEUCOPUS. Journal Of Wildlife Diseases 1995, 31: 345-351. PMID: 8592355, DOI: 10.7589/0090-3558-31.3.345.Peer-Reviewed Original ResearchConceptsEar biopsy samplesPolymerase chain reactionBiopsy samplesBiopsy locationB. burgdorferiBorrelia burgdorferiInfected micePeripheral samplesIndividual miceInfection statusMore tissue samplesMiceTissue samplesHigh concordanceChain reactionOrgan cultureBurgdorferiGreater frequencyEar samplesWhite-footed miceEnzootic areaEarCentral sample
1993
Genetic Identification of a Hantavirus Associated with an Outbreak of Acute Respiratory Illness
Nichol S, Spiropoulou C, Morzunov S, Rollin P, Ksiazek T, Feldmann H, Sanchez A, Childs J, Zaki S, Peters C. Genetic Identification of a Hantavirus Associated with an Outbreak of Acute Respiratory Illness. Science 1993, 262: 914-917. PMID: 8235615, DOI: 10.1126/science.8235615.Peer-Reviewed Original Research
1992
Lymphocytic choriomeningitis virus infection and house mouse (Mus musculus) distribution in urban Baltimore.
Childs J, Glass G, Korch G, Ksiazek T, Leduc J. Lymphocytic choriomeningitis virus infection and house mouse (Mus musculus) distribution in urban Baltimore. American Journal Of Tropical Medicine And Hygiene 1992, 47: 27-34. PMID: 1636880, DOI: 10.4269/ajtmh.1992.47.27.Peer-Reviewed Original Research
1991
Human-rodent contact and infection with lymphocytic choriomeningitis and Seoul viruses in an inner-city population.
Childs J, Glass G, Ksiazek T, Rossi C, Oro J, Leduc J. Human-rodent contact and infection with lymphocytic choriomeningitis and Seoul viruses in an inner-city population. American Journal Of Tropical Medicine And Hygiene 1991, 44: 117-21. PMID: 1672798, DOI: 10.4269/ajtmh.1991.44.117.Peer-Reviewed Original ResearchConceptsLymphocytic choriomeningitis virusSeoul virusRodent-borne virusesHuman-rodent contactHistory of travelInner-city populationDisease clinicRodent exposureLymphocytic choriomeningitisAntibody prevalenceNeutralization testSerological testsAntibodiesVirusHigh rateInfectionRatsMore exposureExposureQuestionnaire responsesChoriomeningitisClinicPrevalenceMicePersons
1989
Serologic evidence of hantaviral infections within small mammal communities of Baltimore, Maryland: spatial and temporal patterns and host range.
Korch G, Childs J, Glass G, Rossi C, LeDuc J. Serologic evidence of hantaviral infections within small mammal communities of Baltimore, Maryland: spatial and temporal patterns and host range. American Journal Of Tropical Medicine And Hygiene 1989, 41: 230-40. PMID: 2570533, DOI: 10.4269/ajtmh.1989.41.230.Peer-Reviewed Original Research
1987
Prospective seroepidemiology of hantaviruses and population dynamics of small mammal communities of Baltimore, Maryland.
Childs J, Glass G, Korch G, LeDuc J. Prospective seroepidemiology of hantaviruses and population dynamics of small mammal communities of Baltimore, Maryland. American Journal Of Tropical Medicine And Hygiene 1987, 37: 648-62. PMID: 2891308, DOI: 10.4269/ajtmh.1987.37.648.Peer-Reviewed Original ResearchConceptsHigh IFA titersProspective seroepidemiological studyIndirect fluorescent antibody titersFluorescent antibody titersEvidence of transmissionTransmission of hantavirusesIndividual blood samplesAntibody titersSeroepidemiological studyIncidence rateAntibody prevalenceBlood samplesIFA titersMean incidenceRatsVirus transmissionHantavirusesMature animalsWhite-footed miceMiceTitersMonthsRodents