2020
Simultaneous cortex-wide fluorescence Ca2+ imaging and whole-brain fMRI
Lake EMR, Ge X, Shen X, Herman P, Hyder F, Cardin JA, Higley MJ, Scheinost D, Papademetris X, Crair MC, Constable RT. Simultaneous cortex-wide fluorescence Ca2+ imaging and whole-brain fMRI. Nature Methods 2020, 17: 1262-1271. PMID: 33139894, PMCID: PMC7704940, DOI: 10.1038/s41592-020-00984-6.Peer-Reviewed Original ResearchConceptsOptical measurementsBrain functionTransgenic murine modelFunctional magnetic resonance imagingMagnetic resonance imagingFluorescent measuresWhole-brain fMRIMurine modelResonance imagingFluorescence Ca2Human brain functionConnectivity strengthBOLD signalBrain activityWidefieldLow frequencyImagingModalitiesTransfer functionMeasurementsCortex
2019
Prefrontal Cortical and Behavioral Adaptations to Surgical Delivery Mediated by Metabolic Principles
Taylor-Giorlando M, Scheinost D, Ment L, Rothman D, Horvath TL. Prefrontal Cortical and Behavioral Adaptations to Surgical Delivery Mediated by Metabolic Principles. Cerebral Cortex 2019, 29: 5061-5071. PMID: 30877804, PMCID: PMC6918927, DOI: 10.1093/cercor/bhz046.Peer-Reviewed Original ResearchConceptsMode of deliverySurgical deliveryLayer 3 pyramidal neuronsAlters mitochondrial dynamicsValues of miceMurine findingsCerebral cortexPyramidal neuronsAdult behaviorHuman neonatesMaze testPrepulse inhibitionSpine synapsesPsychiatric illnessAdult miceNeuronal circuitryAnimal modelsClinical relevanceHuman clinical relevanceUCP-2Prefrontal cortexMitochondrial adaptationsImpaired performanceMitochondrial mechanismsBehavioral phenotypes
2010
A non-rigid registration method for serial lower extremity hybrid SPECT/CT imaging
Suh JW, Scheinost D, Dione DP, Dobrucki LW, Sinusas AJ, Papademetris X. A non-rigid registration method for serial lower extremity hybrid SPECT/CT imaging. Medical Image Analysis 2010, 15: 96-111. PMID: 20869902, PMCID: PMC2988883, DOI: 10.1016/j.media.2010.08.002.Peer-Reviewed Original Research
2009
A Non-rigid Registration Method for Serial microCT Mouse Hindlimb Images
Suh JW, Scheinost D, Dione DP, Dobrucki LW, Sinusas AJ, Papademetris X. A Non-rigid Registration Method for Serial microCT Mouse Hindlimb Images. Lecture Notes In Computer Science 2009, 12: 688-695. PMID: 20426048, PMCID: PMC2856964, DOI: 10.1007/978-3-642-04268-3_85.Peer-Reviewed Original Research