2022
Associations among Household and Neighborhood Socioeconomic Disadvantages, Resting-state Frontoamygdala Connectivity, and Internalizing Symptoms in Youth
Ip KI, Sisk LM, Horien C, Conley MI, Rapuano KM, Rosenberg MD, Greene AS, Scheinost D, Constable RT, Casey BJ, Baskin-Sommers A, Gee DG. Associations among Household and Neighborhood Socioeconomic Disadvantages, Resting-state Frontoamygdala Connectivity, and Internalizing Symptoms in Youth. Journal Of Cognitive Neuroscience 2022, 34: 1810-1841. PMID: 35104356, DOI: 10.1162/jocn_a_01826.Peer-Reviewed Original ResearchConceptsSocioeconomic disadvantageNeighbourhood deprivationResting-state functional connectivityInternalizing symptomsSymptoms 1 yearHigher neighborhood deprivationNeighborhood socioeconomic disadvantageCognitive Development StudyAdolescent Brain Cognitive Development (ABCD) studyEarly interventionBilateral amygdalaElevated symptomsNegative connectivitySymptomsFunctional connectivityMental healthPositive connectivityBaselineHigher internalizing symptomsFrontoparietal networkOFC regionsFunctional couplingDeleterious effectsHigh disadvantageNeeds ratio
2017
Connectome-based Models Predict Separable Components of Attention in Novel Individuals
Rosenberg MD, Hsu WT, Scheinost D, Constable R, Chun MM. Connectome-based Models Predict Separable Components of Attention in Novel Individuals. Journal Of Cognitive Neuroscience 2017, 30: 160-173. PMID: 29040013, DOI: 10.1162/jocn_a_01197.Peer-Reviewed Original ResearchConceptsConnectome-based predictive modelingAttention Network TaskExecutive controlIntrinsic functional organizationRT variabilityANT performanceInfluential modelFunctional connectivityBrain's intrinsic functional organizationComponents of attentionExecutive control scoresResting-state functional connectivityResting-state dataFunctional brain networksFunctional organizationTask-based dataAttentional abilitiesUpcoming stimulusExplicit taskSustained attentionFMRI scanningAttention factorNovel individualsAdditional independent componentNetwork tasks
2014
GABA, Resting-State Connectivity and the Developing Brain
Kwon SH, Scheinost D, Lacadie C, Benjamin J, Myers EH, Qiu M, Schneider KC, Rothman DL, Constable RT, Ment LR. GABA, Resting-State Connectivity and the Developing Brain. Neonatology 2014, 106: 149-155. PMID: 24970028, PMCID: PMC4134402, DOI: 10.1159/000362433.Peer-Reviewed Original ResearchConceptsGamma-aminobutyric acidTerm-equivalent agePreterm infantsGABA concentrationTerm controlsFunctional connectivityMagnetic resonance imaging (MRI) scansFunctional magnetic resonance imaging (fMRI) scansResting-state functional connectivityRegional GABA concentrationTerm control groupResonance imaging scansResting-state connectivityRight frontal lobeConcentration of GABANAA/cholineMagnetic resonance spectroscopyPreclinical dataImaging scansFrontal lobeControl groupInfantsBrainMRI dataAge
2013
Orbitofrontal cortex neurofeedback produces lasting changes in contamination anxiety and resting-state connectivity
Scheinost D, Stoica T, Saksa J, Papademetris X, Constable RT, Pittenger C, Hampson M. Orbitofrontal cortex neurofeedback produces lasting changes in contamination anxiety and resting-state connectivity. Translational Psychiatry 2013, 3: e250-e250. PMID: 23632454, PMCID: PMC3641411, DOI: 10.1038/tp.2013.24.Peer-Reviewed Original ResearchConceptsResting-state connectivityContamination anxietyBrain regionsNF trainingBrain connectivityResting-state functional connectivityFunctional magnetic resonance imaging (fMRI) neurofeedbackPotential of neurofeedbackRelevant brain networksResting-state fMRIDorsolateral prefrontal cortexTarget brain regionsBrain functional architectureUseful therapyLimbic circuitryMatched subjectsOrbitofrontal regionsOrbitofrontal cortexFunctional connectivityPrefrontal cortexHuman emotionsFeedback control tasksSubclinical anxietyAnxiety regulationBrain networks