2023
Test-Retest Reliability of Functional Connectivity in Adolescents With Depression
Camp C, Noble S, Scheinost D, Stringaris A, Nielson D. Test-Retest Reliability of Functional Connectivity in Adolescents With Depression. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2023, 9: 21-29. PMID: 37734478, PMCID: PMC10843837, DOI: 10.1016/j.bpsc.2023.09.002.Peer-Reviewed Original ResearchConceptsMajor depressive disorderIntraclass correlation coefficientTest-retest reliabilityPsychiatric illnessFunctional connectivityMean intraclass correlation coefficientFunctional magnetic resonance imagingMagnetic resonance imagingAverage intraclass correlation coefficientEffect sizeDepressive disorderLongitudinal cohortHealthy individualsMultivariate analysisResonance imagingSymptom severityReproducible biomarkersBrain-behavior associationsGroup differencesDepressionHealthy samplesCorrelation coefficientIllnessAdolescentsBiomarker identificationAltered Brain Dynamics Across Bipolar Disorder and Schizophrenia During Rest and Task Switching Revealed by Overlapping Brain States
Ye J, Sun H, Gao S, Dadashkarimi J, Rosenblatt M, Rodriguez R, Mehta S, Jiang R, Noble S, Westwater M, Scheinost D. Altered Brain Dynamics Across Bipolar Disorder and Schizophrenia During Rest and Task Switching Revealed by Overlapping Brain States. Biological Psychiatry 2023, 94: 580-590. PMID: 37031780, PMCID: PMC10524212, DOI: 10.1016/j.biopsych.2023.03.024.Peer-Reviewed Original ResearchConceptsAberrant brain dynamicsMultiple brain statesBipolar disorderTask-based functional magnetic resonanceFunctional magnetic resonanceAltered brain dynamicsBrain statesTask-based functional magnetic resonance imagingFunctional magnetic resonance imagingMagnetic resonance imagingHealthy control participantsBrain dynamicsSignificant group differencesMagnetic resonanceMultivariate analysisResonance imagingSchizophreniaTime pointsControl participantsGroup differencesNeural mechanismsOlder participantsPreliminary evidenceDynamic alterationsDisorders
2019
A Mass Multivariate Edge-wise Approach for Combining Multiple Connectomes to Improve the Detection of Group Differences
Dadashkarimi J, Gao S, Yeagle E, Noble S, Scheinost D. A Mass Multivariate Edge-wise Approach for Combining Multiple Connectomes to Improve the Detection of Group Differences. Lecture Notes In Computer Science 2019, 11848: 64-73. DOI: 10.1007/978-3-030-32391-2_7.Peer-Reviewed Original ResearchGroup differences
2018
Craving to Quit: A Randomized Controlled Trial of Smartphone App–Based Mindfulness Training for Smoking Cessation
Garrison KA, Pal P, O’Malley S, Pittman BP, Gueorguieva R, Rojiani R, Scheinost D, Dallery J, Brewer JA. Craving to Quit: A Randomized Controlled Trial of Smartphone App–Based Mindfulness Training for Smoking Cessation. Nicotine & Tobacco Research 2018, 22: 324-331. PMID: 29917096, PMCID: PMC7297096, DOI: 10.1093/ntr/nty126.Peer-Reviewed Original ResearchConceptsMindfulness trainingExperience samplingPreliminary evidenceSmartphone appPoint prevalence abstinence ratesMindfulnessSmoking cessationTreatment startersSmoking ratesGroup differencesGroup interactionCravingStrong positive associationAbstinence ratesTrainingTreatment completionPositive associationControlled TrialsTreat approachSmokingTrialsCigarettesMonthsAppsAssociation
2017
Altered functional connectivity to stressful stimuli in prenatally cocaine-exposed adolescents
Zakiniaeiz Y, Yip SW, Balodis IM, Lacadie CM, Scheinost D, Constable RT, Mayes LC, Sinha R, Potenza MN. Altered functional connectivity to stressful stimuli in prenatally cocaine-exposed adolescents. Drug And Alcohol Dependence 2017, 180: 129-136. PMID: 28888152, PMCID: PMC5808433, DOI: 10.1016/j.drugalcdep.2017.07.030.Peer-Reviewed Original ResearchConceptsPrenatal cocaine exposureNeutral-relaxing conditionsPCE adolescentsParietal connectivityConnectivity analysisSensory areasAdolescent brain functionFunctional magnetic resonance imagingCue interaction effectsIntrinsic connectivity analysesMedial prefrontal areasSeed-based connectivity analysisSubstance Use InitiationAltered functional connectivityAppetitive cuesObesity vulnerabilityPCE statusNeural responsesCorticolimbic connectivityPrefrontal areasFunctional connectivityCraving scoresUtero drug exposureGroup differencesLess connectivity
2014
The impact of image smoothness on intrinsic functional connectivity and head motion confounds
Scheinost D, Papademetris X, Constable RT. The impact of image smoothness on intrinsic functional connectivity and head motion confounds. NeuroImage 2014, 95: 13-21. PMID: 24657356, PMCID: PMC4076413, DOI: 10.1016/j.neuroimage.2014.03.035.Peer-Reviewed Original ResearchConceptsResting-state functional magnetic resonance imagingWhole-brain functional organizationFunctional magnetic resonance imagingIntrinsic functional connectivityMagnetic resonance imagingFunctional connectivity studiesResonance imagingRs-fMRIFunctional connectivityClinical populationsGroup differencesConnectivity studiesHead motionFunctional organizationHead movementsRecent studiesBOLD signal and functional connectivity associated with loving kindness meditation
Garrison KA, Scheinost D, Constable RT, Brewer JA. BOLD signal and functional connectivity associated with loving kindness meditation. Brain And Behavior 2014, 4: 337-347. PMID: 24944863, PMCID: PMC4055184, DOI: 10.1002/brb3.219.Peer-Reviewed Original ResearchConceptsPCC/PCuFunctional connectivityGreater functional connectivityIntrinsic connectivityPosterior cingulate cortex/precuneusParahippocampus/hippocampusSeed-based connectivity analysisBOLD signalBlood oxygen level-dependent (BOLD) signalGroup differencesIntrinsic connectivity distributionLevel-dependent signalKindness meditationCortical midline regionsDefault mode networkFunctional magnetic resonanceInsula lobeInferior frontal gyrusSilent repetitionBrain regionsLeft inferior frontal gyrusFrontal gyrusMidline regionSelf-related processingMode network