2000
The Immunologically Protective P-4 Antigen ofLeishmania Amastigotes A DEVELOPMENTALLY REGULATED SINGLE STRAND-SPECIFIC NUCLEASE ASSOCIATED WITH THE ENDOPLASMIC RETICULUM*
Kar S, Soong L, Colmenares M, Goldsmith-Pestana K, McMahon-Pratt D. The Immunologically Protective P-4 Antigen ofLeishmania Amastigotes A DEVELOPMENTALLY REGULATED SINGLE STRAND-SPECIFIC NUCLEASE ASSOCIATED WITH THE ENDOPLASMIC RETICULUM*. Journal Of Biological Chemistry 2000, 275: 37789-37797. PMID: 10969068, DOI: 10.1074/jbc.m002149200.Peer-Reviewed Original ResearchConceptsEndoplasmic reticulumSpecific nuclease activityBlot analysisImmunofluorescence microscopic analysisIntracellular amastigote stageProtein sequence dataSingle-strand nucleasePeripheral blood mononuclear cellsSouthern blot analysisNorthern blot analysisBlood mononuclear cellsMembrane proteinsRNA stabilitySubcellular localizationFuture vaccine studiesDNA repairSequence dataTerminal domainAmerican cutaneous leishmaniasisSequence analysisNuclease activityAmastigote stagePromastigote stageSpecific nucleasesT helper
1983
Monoclonal antibodies specific for Leishmania tropica. I. Characterization of antigens associated with stage- and species-specific determinants.
Jaffe C, McMahon-Pratt D. Monoclonal antibodies specific for Leishmania tropica. I. Characterization of antigens associated with stage- and species-specific determinants. The Journal Of Immunology 1983, 131: 1987-93. PMID: 6194223, DOI: 10.4049/jimmunol.131.4.1987.Peer-Reviewed Original ResearchConceptsSpecies-specific determinantsPromastigote stageDifferent cell surface proteinsCell surface proteinsMonoclonal antibody bindsMembrane-enriched preparationsCell surface componentsL. tropica complexAdditional proteinsKilodalton proteinClone TTrypanosoma cruziSurface proteinsProteinMonoclonal antibodiesIntact promastigotesSurface componentsSolubilized 125IL. donovaniL. braziliensis braziliensisMajor promastigotesL. mexicana amazonensisPromastigotesI. CharacterizationCruzi