2012
Biomonitoring Hexamethylene Diisocyanate (HDI) Exposure Based on Serum Levels of HDI-Specific IgG
Wisnewski AV, Stowe MH, Nerlinger A, Opare-addo P, Decamp D, Kleinsmith CR, Redlich CA. Biomonitoring Hexamethylene Diisocyanate (HDI) Exposure Based on Serum Levels of HDI-Specific IgG. Annals Of Work Exposures And Health 2012, 56: 901-910. PMID: 22449630, PMCID: PMC3471419, DOI: 10.1093/annhyg/mes024.Peer-Reviewed Original ResearchConceptsPersonal protective equipmentSkin exposureExposure surveillanceSpecific serum immunoglobulin GHexamethylene diisocyanate exposureSerum IgG levelsSerum immunoglobulin GNight shift workEnzyme-linked immunosorbentAdverse health effectsAsthma historyDiisocyanate exposureIgG levelsSerum levelsIgG titersChemical allergensPPE useImmune responseRespirator useIsocyanate exposureExposure biomarkersPractical biomarkersBasic demographicsHigh titersHygiene efforts
2007
Developments in laboratory diagnostics for isocyanate asthma
Wisnewski AV. Developments in laboratory diagnostics for isocyanate asthma. Current Opinion In Allergy And Clinical Immunology 2007, 7: 138-145. PMID: 17351466, PMCID: PMC3131002, DOI: 10.1097/aci.0b013e3280895d22.Peer-Reviewed Original ResearchConceptsIsocyanate asthmaSpecific inhalation challengeCause of asthmaEnzyme-linked immunosorbentBiomarkers of exposureGold standard testInhalation challengeOccupational asthmaAsthma pathogenesisRisk factorsSpecialized centersAsthmaWorkplace exposuresAsthma diagnosticsEfficient laboratory testsHuman IgELaboratory testsClinical diagnosisContemporary laboratory testsLaboratory diagnosticsSubset of workersIgEDisease developmentExposureCause
1991
Screening of murine monoclonal antibodies against living schistosomula of Schistosoma mansoni by radioimmunoassay
Wiest P, Wisnewski A, Johnson J, Ramirez B, Kresina T, Olds G. Screening of murine monoclonal antibodies against living schistosomula of Schistosoma mansoni by radioimmunoassay. International Journal For Parasitology 1991, 21: 449-454. PMID: 1917285, DOI: 10.1016/0020-7519(91)90102-d.Peer-Reviewed Original ResearchConceptsMurine monoclonal antibodiesSurface antigenSoluble adult worm antigenSchistosoma mansoniMonoclonal antibodiesS. mansoni paramyosinS. mansoni infectionSoluble egg antigenAdult worm antigenEnzyme-linked immunosorbentMansoni infectionEgg antigenLung stageWorm antigenS. mansoniSecrete antibodiesAntigenSchistosomulaAdult wormsAntibodiesRadioimmunoassayMansoniImmunoblot analysisOld parasitesMurine hybridomas