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The Gut-brain Axis: a Novel Target for Treating Behavioral Alterations in Obesity (CIDO OEA)


Mental Health & Behavioral Research | Obesity & Weight Control

Phase I

What is the purpose of this trial?

The aims of this project are to determine if dietary supplementation with NOPE-EGCG (PhosphoLeantm, 30mg NOPE+20mg EGCG per capsule) can:

  • rescue striatal function,
  • increase adherence to a diet,
  • reduce weight-gain after a diet,
  • improve performance on impulsivity, go/no-go tasks, and negative outcome learning, and
  • shift fat and sweet preference in overweight/obese human subjects in a double-blind cross-over design.
  • Trial with
    Yale University School of Medicine
  • Start Date
  • End Date

I'm interested in volunteering

If you would prefer to contact a member of the Help us Discover team about this trial and other similar trials, please email or call 877.978.8343

  • Last Updated
  • Study HIC