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Switching to Potential Reduced Exposure Products in Adult Smokers (JUUL)


Addictive Behaviors | Mental Health & Behavioral Research | Tobacco Addiction

What is the purpose of this trial?

Brief Summary:

This study aims to assess the feasibility, acceptability, and the potential harm reduction of switching to potentially lower risk, non-combustible tobacco products in adult smokers. Part One of this study aims to assess the interest of current smokers in switching to an e-cigarette device (i.e. JUUL) compared to alternative non-combustible tobacco products (i.e. smokeless tobacco/snus) and/or medicinal nicotine via survey. Part Two will consist of a pilot study of 50 non-treatment seeking adult smokers with medical co-morbidities to investigate within-person changes in smoking behavior as a result of switching to different concentrations a nicotine salt electronic cigarette product (i.e. JUUL, 3% and 5% nicotine concentration). Additionally, by measuring bio-markers of tobacco exposure from baseline, this will allow the study to assess the potential for harm reduction in switching from cigarettes to an e-cigarette device.

  • Trial with
    National Institute on Drug Abuse (NIDA)
  • Start Date
  • End Date

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  • Last Updated
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