Diseases of the Cardiovascular System

Mechanisms of Diuretic Resistance in Heart Failure (MsDR)

Volunteers
Health Professionals

What is the purpose of this trial?

This study will employ a randomized order, double-blind, repeated measures dose ranging design. This design was chosen in order to generate multiple within-subject serial loop diuretic dose response exposures. The overall study schema will include 50 diuretic resistant HF patients and 25 diuretic responsive heart failure (HF) patients.

Trial with
National Institute of Diabetes and Digestive & Kidney Diseases (NIDDK)
Ages
18 years and older
Gender
Both

Find out more about who can participate in this trial

Contact Information

For more information about this study, including how to volunteer, contact Jeffrey Testani

jeffrey.testani@yale.edu

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Principal Investigator

Jeffrey Testani, MD, MTR
Associate Professor of Medicine; Director of Heart Failure Research, Cardiovascular Medicine; Co-Director Heart & Vascular Center Clinical Research, Heart & Vascular Center

Sub-Investigators

Last Updated
04/04/2024
Study HIC
#2000032328