Imaging Tobacco Smoking Withdrawal using [11C]PHNO
Mental Health & Behavioral Research | Tobacco Addiction
What is the purpose of this trial?
This research study is designed to look at the involvement of the dopamine systems in smoking, and the way people feel and think. This study will help us further examine brain chemistry and nicotine addiction. This study accepts both healthy non-smoker and healthy smoker subjects. Healthy non-smoker subjects will receive 1 PET scan with the radiotracer PHNO along with an amphetamine challenge and 1 mri .
Healthy smoker subjects will be asked to quit smoking for up to 8 weeks and will receive up to 2 PET scans with the radiotracer PHNO along with 2 amphetamine challenges and 2 mris over the course of their abstinence.
- Ages18 years - 55 years
- Trial withNational Institute on Drug Abuse (NIDA)
- Start Date09/20/2017
- End Date09/30/2022
- Last Updated07/15/2021
- Study HIC#2000021470