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Imaging Synaptic Density in Cocaine and Opiate Addiction In Vivo using 11C-UCB-J PET


Addictive Behaviors

Phase Pilot

What is the purpose of this trial?

Looking for individuals between 21 and 55 years old currently abusing opiates and not taking medication for it (i.e., Methadone or Buprenorphine). This research study is designed to explore how opiate addiction influences synaptic density. This relationship will be explored in the brain’s prefrontal cortex, an area important in decision-making and impulsivity. In this study, subjects will participate in one 11C-UCB-J Positron Emission Tomography (PET) scan and one structural and functional resting state Magnetic Resonance Imaging (MRI) scan.

This is an inpatient study up to 4 weeks that requires managed abstinence.

  • Trial with
    National Institute on Drug Abuse (NIDA)
  • Start Date
  • End Date

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If you would prefer to contact a member of the Help us Discover team about this trial and other similar trials, please email or call 877.978.8343

  • Last Updated
  • Study HIC