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Imaging Synaptic Density in Cocaine and Opiate Addiction In Vivo using 11C-UCB-J PET

Conditions

Addictive Behaviors

Phase Pilot

What is the purpose of this trial?

Looking for individuals between 21 and 55 years old currently abusing opiates and not taking medication for it (i.e., Methadone or Buprenorphine). This research study is designed to explore how opiate addiction influences synaptic density. This relationship will be explored in the brain’s prefrontal cortex, an area important in decision-making and impulsivity. In this study, subjects will participate in one 11C-UCB-J Positron Emission Tomography (PET) scan and one structural and functional resting state Magnetic Resonance Imaging (MRI) scan.

This is an inpatient study up to 4 weeks that requires managed abstinence.

  • Trial with
    Peter F. McManus Charitable Trust
  • Start Date
    01/29/2019
  • End Date
    10/31/2022

I'm interested in volunteering

If you would prefer to contact a member of the Help us Discover team about this trial and other similar trials, please email helpusdiscover@yale.edu or call 877.978.8343

  • Last Updated
    07/15/2021
  • Study HIC
    #2000021843