Imaging Synaptic Density in Cocaine and Opiate Addiction In Vivo using 11C-UCB-J PET
Conditions
Addictive Behaviors
Phase Pilot
Volunteers
Health Professionals
What is the purpose of this trial?
Looking for individuals between 21 and 55 years old currently abusing opiates and not taking medication for it (i.e., Methadone or Buprenorphine). This research study is designed to explore how opiate addiction influences synaptic density. This relationship will be explored in the brain’s prefrontal cortex, an area important in decision-making and impulsivity. In this study, subjects will participate in one 11C-UCB-J Positron Emission Tomography (PET) scan and one structural and functional resting state Magnetic Resonance Imaging (MRI) scan.
This is an inpatient study up to 4 weeks that requires managed abstinence.
- Trial withNational Institute on Drug Abuse (NIDA)
- Start Date01/29/2019
- End Date01/01/2024
For more information about this study, contact:
Jessica Costeines
I'm interested in volunteering
If you would prefer to contact a member of the Help us Discover team about this trial and other similar trials, please email helpusdiscover@yale.edu or call 877.978.8343
Principal Investigator
Sub-Investigators
- Last Updated04/19/2022
- Study HIC#2000021843