Imaging dopamine mediated effects of stress on inhibitory control
Diseases of the Nervous System
What is the purpose of this trial?
You are invited to take part in our research study of the brain, the immune system, and cigarette smoking. We will use brain imaging (PET and MRI) to determine if activation of the immune system leads to greater chance of relapse to smoking. After agreeing to participate in this research, you will receive a low dose of either lipopolysaccharide (LPS) or placebo on scan days and methylphenidate (Ritalin) on PET scan days. There are three PET scans and two MRI scans.
- Ages18 years - 55 years
- Trial withNational Institute on Drug Abuse (NIDA)
- Start Date10/30/2018
- End Date03/01/2023
- Last Updated07/15/2021
- Study HIC#2000023863