NCI-MATCH: Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors or Lymphomas
Conditions
Anus | Bones and Joints | Brain and Nervous System | Breast - Female | Breast - Male | Colon | Corpus Uteri | Esophagus | Eye and Orbit | Hodgkin's Lymphoma | Kaposi's sarcoma | Kidney | Larynx | Lip, Oral Cavity and Pharynx | Liver | Lung | Lymphoid Leukemia | Melanoma, skin | Non-Hodgkin's Lymphoma | Other Digestive Organ | Other Endocrine System | Other Female Genital | Other Male Genital | Other Respiratory and Intrathoracic Organs | Other Skin | Other Urinary | Ovary | Pancreas | Prostate | Rectum | Small Intestine | Soft Tissue | Stomach | Thyroid | Cervix | Urinary Bladder
Phase II
Volunteers
Health Professionals
What is the purpose of this trial?
This phase II trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have progressed following at least one line of standard treatment or for which no agreed upon treatment approach exists. Genetic tests look at the unique genetic material (genes) of patients' tumor cells. Patients with genetic abnormalities (such as mutations, amplifications, or translocations) may benefit more from treatment which targets their tumor's particular genetic abnormality. Identifying these genetic abnormalities first may help doctors plan better treatment for patients with solid tumors or lymphomas.
- Ages18 years and older
- GenderBoth
- Trial withNational Cancer Institute (NCI)
- Start Date08/08/2016
- End Date06/30/2022
I'm interested in volunteering
If you would prefer to contact a member of the Help us Discover team about this trial and other similar trials, please email helpusdiscover@yale.edu or call 877.978.8343
Principal Investigator
Sub-Investigators
- Alessandro Santin, MD
- Alessia Donadio, MD
- Anamika Katoch, MD
- Andrea Brennan
- Andrea Martelli
- Andrea Silber, MD
- Anne Chiang, MD, PhD
- Armand Russo, MD
- Ashita Talsania, MRCP, MBBS
- Barbara Burtness, MD
- Benjamin Newton, MD
- Brooke Chaves
- Carrie Fijal
- Daniel P. Petrylak, MD
- David Witt, MD
- Elena Ratner, MD
- Farzana Pashankar, MD, MRCP
- Frederick Wilson, MD, PhD
- Hari Deshpande, MD
- Harold Tara Jr, MD
- James Vredenburgh, MD
- Jason Haldas, MD
- Jaykumar Thumar, MBBS, MD
- Jeremy Kortmansky, MD
- Jill Lacy, MD
- Joachim Baehring, MD
- Johanna LaSala, MD
- Joseph Kim, MD
- Juan Vasquez, MD
- Justin Persico, MD
- Katherine Harvey, MD, MPH
- Kert Sabbath, MD, FACP
- Khanh Nguyen, MD
- Kristen Hoxie
- Lajos Pusztai, MD, DPhil
- Madeline Santiago
- Marianne Davies, NP, DNP, MSN, BSN
- Masoud Azodi, MD
- Matthew Dodd, PA-C
- Michael Cecchini, MD
- Michael Cohenuram, MD
- Michael Hurwitz, PhD, MD
- Neal Fischbach, MD
- Ninani Kombo, MD
- Pawan Karanam, MD
- Peter Schwartz, MD
- Prasanna Ananth, MD, MPH
- Roy S. Herbst, MD, PhD
- Sarah Goldberg, MD, MPH
- Sarah Mougalian, MD
- Stacey Stein, MD
- Stephen Lattanzi, MD
- Su Hsien Lim, MD
- Susan Rabinowe, MD
- Syed Bilgrami, MBBS
- Victor Chang, MD
- Wajih Kidwai, MD, FACP
- Xuanthao Thi Nguyen
- Zia Rahman, MD
- Last Updated07/15/2021
- Study HIC#1507016151