Digoxin In Alcohol Associated Hepatitis
Hepatitis | Diseases of the Digestive System - Liver
What is the purpose of this trial?
Acute alcohol associated hepatitis (also known as AlcHep) is an illness that results from alcohol consumption. Patients with the severe form of AlcHep have up to 40% mortality within 6 months after diagnosis. There are no approved drugs to treat AlcHep. Pre-clinical studies show that digoxin, a drug currently used in the treatment of heart failure and other heart conditions, can improve liver injury associated with alcohol use. The main goal of this study is to assess the feasibility of conducting a future large clinical trial with respect to patient recruitment, digoxin administration and dose adjustment in patients admitted to the hospital with severe AlcHep.
- Ages21 years - 65 years
- Trial withYale University School of Medicine
- Start Date10/12/2021
- End Date02/28/2023
- Last Updated11/03/2021
- Study HIC#2000030659