Psychiatric disorders share an underlying genetic basis
Thomas Fernandez, MD, Assistant Professor in the Child Study Center and of Psychiatry, and Christopher Pittenger, MD, PhD, Associate Professor of Psychiatry, contributed to a paper published in Science that explores the genetic connections between disorders of the brain at a scale that far eclipses previous work on the subject.
How autism may stem from problems with prediction
A ‘predictive coding’ theory of autism suggests that many of the condition’s hallmark traits occur when sensory input overrides expectation in the brain. Yale researchers, Katarzyna Chawarska, James McPartland and Philip Corlett, are featured.Source: Spectrum
College students with autism have high rate of suicidal thoughts
Over the next decade, about 247,000 young adults with autism spectrum disorder (ASD) are expected to enroll in universities, colleges, or technical/vocational schools. Because post-secondary education is expected to present new challenges to individuals with ASD, new scholarship is being conducted to assess how ready post-secondary education is to serve a larger population with ASD.
Study testing first medication to treat symptoms of autism
Dr. Roger Jou, a psychiatrist at the Yale Child Study Center who treats and works with those on the autism spectrum, is testing a new medication, in a nationwide clinical trial, which could become the first drug to increase the ability of young people with autism to connect with others and to overcome the other symptoms of the disorder.Source: The New Haven Register
Multicenter Trial Management Unit Expands the Scope of Research at Yale
In the past, Yale investigators who led multicenter trials had to put together ad hoc study teams, relying on unconnected siloed services to carry out their research. At the end of these trials, these teams, which had compiled so much experience and knowledge, disbanded and their knowledge was lost. This system was inefficient and put Yale at a disadvantage when competing with other institutions for grants for multicenter studies.
Yale launches five-year study of origins of autism
Yale researchers will study the development of functional brain connectivity during late pregnancy to early adolescence thanks to a five-year, $12.4 million grant from Autism Centers of Excellence Program, part of efforts by the National Institutes of Health to understand the origins of autism spectrum disorders (ASD).
Participating in a Clinical Trial Leads to a Teen’s Diagnosis and Treatment
On a warm spring day, Rayford Bromley, 13, sprawled on a bench in the Yale Child Study Center, chatting about school, his friends, and a bonfire he had been invited to attend. This was a big change from just a few months ago. Anxious and withdrawn, Rafe had been struggling, wanting to make friends but not knowing how to go about it.
Combination approach may help combat autism
The hormone oxytocin, the so-called hug hormone or cuddle chemical, has more nicknames than proven medical uses. However, oxytocin may benefit children with autism spectrum disorders if receptors for opioids — brain chemicals activated by drugs such as heroin that tend to disconnect people socially — are also blocked, Yale researchers report the week of May 1 in the journal Proceedings of the National Academy of Sciences.
A Childhood Surrounded by Science
For Amy Vatner and her three young boys, participating in clinical trials at Yale has meant becoming part of a community. “My kids are now turning nine, seven, and three and a half,” Vatner says, “and they have been involved in studies at Yale for their entire lives.”
Moreno De Luca: More testing needed to identify genetic abnormalities with autism spectrum disorder
Daniel Moreno De Luca, MD, MSc, a fourth-year resident in the Yale Department of Psychiatry, is advocating for more children to undergo tests to identify genetic abnormalities that are highly associated with autism-spectrum disorder.