Long term Structural and Functional Neural Changes Following a Single Infusion of Ketamine in PTSD
Or Duek, PhD, assistant professor adjunct of psychiatry, and Ilan Harpaz-Rotem, PhD, professor of psychiatry and of psychology, are first and senior authors, respectively of a study published in Neuropsychopharmacology that tests the potential of a single infusion of ketamine, followed by brief exposure therapy, to enhance post-retrieval extinction of post-traumatic stress disorder trauma memories.Source: Neuropsychopharmacology
Yale Researcher Awarded $40 Million to Lead New VA Study to Evaluate Esketamine for Treatment Resistant Depression
Somaia Mohamed, MD, PhD, associate professor of psychiatry, is lead co-investigator of a Department of Veterans Affairs (VA) study that has been awarded $40 million to evaluate the effectiveness of a novel antidepressant medicine, esketamine, for veterans and others with treatment resistant depression (TRD).
Study: Daily Consumption of a High-Fat, High-Sugar Snack Alters Reward Circuits in Brain
Snacks high in sugar and fat are great for an occasional treat, but when enjoyed daily for several weeks they can rewire the brain and trigger a shift in eating preferences away from low-fat food, according to a new study in Cell Metabolism.
Yale Study: Regular Cannabis Use is Associated With History of Childhood and Lifetime Trauma
Anahita Bassir Nia, MD; Jeremy Weleff, DO; Nia Fogelman, PhD; and Rajita Sinha, PhD, are co-authors of a paper in Journal of Psychiatric Research that found people who use cannabis regularly have higher rates of childhood trauma and lifetime trauma.Source: Journal of Psychiatric Research
Calhoun Accepted to American Medical Association-Satcher Health Leadership Institute Medical Justice in Advocacy Fellowship
Amanda Calhoun, MD, MPH, a resident in the Albert J. Solnit Integrated Adult/Child Psychiatry program, has been accepted to the American Medical Association (AMA)-Satcher Health Leadership Institute (SHLI) Medical Justice in Advocacy Fellowship.
Four Yale Researchers Honored at the 2022 Association for Clinical and Translational Science Awards
The collaboration that advanced the discovery of ketamine as a treatment for depression was among four Yale award winners at the Association for Clinical and Translational Science (ACTS) annual meeting held in Chicago from April 20 through 22.
WHRY Funds Study on How CBD Affects the Brain
Women’s Health Research at Yale announced funding to investigate how the presumably non-intoxicating cannabis ingredient cannabidiol (CBD) affects the brain, and if it affects women and men differently. CBD use is growing in popularity exponentially, yet the safety and effectiveness of this non-regulated category of products are unknown.
Stress and Resilience Town Halls Are Being Offered
The Yale Department of Psychiatry continues to offer virtual “Stress and Resilience Town Halls” over Zoom that are open to all faculty, residents, and staff at Yale School of Medicine and Yale New Haven Health. Virtual meetings will run for up to an hour. Individuals can attend as frequently as they like.
Yale Scientists Awarded $8.4M Grant to Develop Treatments for Women With Problem Drinking
Yale Department of Psychiatry scientists have been awarded a five-year, $8.4 million federal grant to establish a new research center at Yale that will develop treatments to help women with problem drinking.
How the Brain Helps Us Make Good Decisions — and Bad Ones
A prevailing theory in neuroscience holds that people make decisions based on integrated global calculations that occur within the frontal cortex of the brain. However, Yale researchers have found that three distinct circuits connecting to different brain regions are involved in making good decisions, bad ones, and determining which of those past choices to store in memory, they report June 25 in the journal Neuron.
Biomarker Reveals PTSD Sufferers at Risk of Suicide
The risk of suicide among individuals with post-traumatic stress disorder (PTSD) is much higher than the general population, but identifying those individuals at greatest risk has been difficult. However, a team at Yale has discovered a biological marker linked to individuals with PTSD who are most likely to think about suicide, the researchers report May 13 in the journal Proceedings of the National Academy of Sciences.
Speeding Treatment Blunts the Worst of Schizophrenia
An interdisciplinary program called Specialized Treatment Early in Psychosis, founded by Vinod Srihari, MD, is helping speed treatment of schizophrenia. How quickly the condition is diagnosed and treated can determine a patient’s odds of living a relatively normal, albeit medicated, life.Source: Yale Medicine
Yonkers, Forray Co-PIs on New Grant to Study Medication Delivery for Pregnant Women with Opioid Use Disorders
Kimberly Yonkers, MD, Professor of Psychiatry, of Epidemiology (Chronic Diseases) and of Obstetrics, Gynecology, and Reproductive Services, and Ariadna Forray, MD, Associate Professor of Psychiatry, are co-principal investigators on a new $5.5 million grant to study models to improve delivery of office-based medication treatment for pregnant women with opioid use disorder in prenatal clinics.
Yale Researchers Study Association of Economic Status and Educational Attainment with PTSD
Renato Polimanti, PhD, MSc, Assistant Professor of Psychiatry, is the lead author of a genome-wide study that found economic status mediates negative associations of cognitive ability and educational attainment in people with posttraumatic stress disorder (PTSD).
Yale Joins More Than 100 Organizations in Countering the Opioid Epidemic
Yale School of Medicine is among more than 100 organizations across the U.S.—including community organizations, hospital and medical systems, academia, nonprofits, and health professional societies—to join the National Academy of Medicine (NAM) in declaring their commitment to reversing national trends in opioid misuse and overdose.
Scientists Restore Some Functions in a Pig’s Brain Hours After Death
Circulation and cellular activity were restored in a pig’s brain four hours after its death, a finding that challenges long-held assumptions about the timing and irreversible nature of the cessation of some brain functions after death, Yale scientists report in the journal Nature.
Desai to be honored with early career award from American Psychological Association
Miraj Desai, PhD, Instructor at the Yale Program for Recovery and Community Health at Yale School of Medicine, has been chosen to receive the Distinguished Early Career Contributions in Qualitative Inquiry Award from Division 5 of the American Psychological Association (Division of Quantitative and Qualitative Methods).
Yale Researchers Awarded $40 Million to Study Opioid Addiction Treatments
Yale School of Medicine faculty have been awarded $40 million in grants to study medication treatment for veterans with opioid addiction. Drs. Ismene Petrakis and Sandra Springer are co-principal investigators leading the research, which is supported by the Veterans Affairs (VA) Cooperative Study.