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Science and Safety Committee (SSC)


The role of the Science and Safety Committee is to evaluate the scientific merit of clinical research protocols including novelty of the science, impact of the science on the subject area of the protocol, and justification of the utilization of human subjects to answer the scientific question(s) of the protocol. The Committee is also charged with the evaluation of the safety of the protocol with regard to inclusion/exclusion criteria, minimization of risks/maximization of benefits, justification of the research procedures to be utilized, and plans for the provision of overall medical and nursing care for subjects.

Protocols Requiring SSC Review
Requests for YCCI services are accepted on a continuous basis via the YCCI Intake Form. For general questions regarding YCCI services, please contact High Risk and Phase I studies planning to utilize YCCI services will be provided to the SSC co-chairs to determine if review is required at a convened SSC meeting. The Principal Investigator will be informed if a full committee review is needed along with any relevant information. When approved by SSC, the PI will receive an approval letter from YCCI via email.

For additional information regarding whether or not a protocol needs to go through the SSC please email

Science and Safety Committee (SSC)

For information contact:

Niece Hanna, MSW
Research Oversight Committee Regulatory Analyst 
Yale Center for Clinical Investigation 
2 Church Street South, Suite 409