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Gail D'Onofrio, MD, MS

Albert E. Kent Professor of Emergency Medicine and Professor of Epidemiology (Chronic Diseases); Chair, Department of Emergency Medicine

“Academic faculty members need to be very proactive in their career trajectory,” said Gail D’Onofrio, MD, MS. “They need someone to help them navigate the academic waters. It’s an active process.”

Dr. D’Onofrio has extensive experience mentoring dozens of young investigators from multiple disciplines at Yale and other institutions. She is Co-PI with Patrick O’Connor, MD, on a training grant from the National Institute on Drug Abuse (NIDA) to train Fellows from such fields as emergency medicine, internal medicine, obstetrics/gynecology, and pediatrics to become independent investigators focusing on drug use, addiction, and HIV prevention in general medical settings. She also leads grants from the Substance Abuse and Mental Health Services Administration (SAMSHA) to train primary care residents and students in the professions of medicine, nursing, social work, and counseling. Her mentees include researchers from fellow-CTSA sites like New York University and the University of North Carolina.

As a mentor, Dr. D’Onofrio has a hands-on approach in helping junior colleagues align their interests with fundable research proposals; write grants; establish a professional network at Yale and in the wider community; and balance professional activities with scholarship.

Dr. D’Onofrio is a national expert on heart disease in women and internationally known for her work in screening emergency department patients for alcohol and other drug use. A recent study published in the Journal of the American Medical Association was the first-known randomized trial comparing three treatment strategies for opioid-dependent patients receiving emergency care. Eighty percent of those treated with buprenorphine in the emergency department were engaged in treatment 30 days later and were less likely to use illicit opioids. Dr. D’Onofrio, co-PI David Fiellin, MD, and other colleagues are currently developing plans to expand this treatment model to multiple sites.

Dr. D’Onofrio is committed to expanding the cadre of clinical researchers at Yale University. Working with Yale-New Haven Hospital—the fourth largest hospital in the United States—she said “we have the opportunity to enroll patients with a wide range of diseases and to work with community and outreach programs to improve the health of the public. Centralized CTSA-supported resources are critical to these efforts.”