Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response
Mental Health & Behavioral Research
What is the purpose of this trial?
The proposed study will assess the combined effect of perampanel and ketamine on the anti-depressant response in individuals with treatment resistant depression. The purpose of this study is to test the hypothesis that stimulation of Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid receptors (AMPAR) is critical to the anti-depressant response of ketamine.
- Ages21 years - 65 years
- Trial withYale University School of Medicine
- Start Date02/12/2018
- End Date06/30/2032
- Last Updated07/15/2021
- Study HIC#2000021345