A Randomized Phase III Trial of Induction/Consolidation Atezolizumab (NSC #783608) + SBRT Versus SBRT Alone in High Risk, Early Stage NSCLC
Volunteers
Health Professionals
What is the purpose of this trial?
This trial studies how well atezolizumab added to the usual radiation therapy works in treating patients with stage I-IIA non-small cell lung cancer. Immunotherapy with monoclonal antibodies, such as atezolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Radiation therapy, such as stereotactic body radiation therapy, uses special equipment to position a patient and deliver radiation to tumors with high precision. This method can kill tumor cells with fewer doses over a shorter period and cause less damage to normal tissue. Giving atezolizumab and radiation therapy may work better than radiation therapy alone in treating patients with early non-small cell lung cancer.
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Principal Investigator
Sub-Investigators
- Abhijit Patel, MD, PhD
- Allison Campbell, MD, PhD
- Anca Bulgaru, MD
- Andrea Brennan
- Anne Chiang, MD, PhD
- Armand Russo, MD
- Benjamin Newton, MD
- Beverly Drucker, MD, PhD
- Bruce A. McGibbon, MD
- Carrie Fijal, MSN, AGPCNP-BC, OCN
- Catherine Wei, MD
- Christin A. Knowlton, MD, MA
- D. Barry Boyd, MD, MS
- David Witt, MD
- Elan Gorshein, DO, JD, MPH
- Emily Duffield, APRN
- Francesca Montanari, MD
- Frederick Wilson, MD, PhD
- Harold Tara Jr, MD
- James E. Hansen, MD, MS
- Jane Kanowitz, MD
- Jason Haldas, MD
- Jeremy Kortmansky, MD
- Johanna LaSala, MD
- John Glendening
- Justin Persico, MD
- Kathleen Fenn, MD
- Kenneth B. Roberts, MD
- Kevin Du, MD, PhD, MSCI
- Kimberly L. Johung, MD, PhD
- Kristen Hoxie
- Larisa Fleysher
- M. Sung Lee, MD
- Marianne Davies, NP, DNP, MSN, BSN
- Melissa Rasar Young, MD, PhD
- Michael Cohenuram, MD
- Nadine Housri, MD
- Neal Fischbach, MD
- Renee Moye
- Robert Legare, MD
- Roy S. Herbst, MD, PhD
- Sarah Carlson
- Sarah Goldberg, MD, MPH
- Scott Gettinger, MD
- Shari Damast, MD
- Stephen Lattanzi, MD
- Su Hsien Lim, MD
- Thomas Hayman, MD, PhD
- Virginia Syombathy
- Wajih Kidwai, MD, FACP
- Yi An, MD
- Last Updated02/20/2024
- Study HIC#2000030031