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Imaging Tobacco Smoking Withdrawal using [11C]PHNO

Conditions

Mental Health & Behavioral Research | Tobacco Addiction

What is the purpose of this trial?

This research study is designed to look at the involvement of the dopamine systems in smoking, and the way people feel and think. This study will help us further examine brain chemistry and nicotine addiction. This study accepts both healthy non-smoker and healthy smoker subjects. Healthy non-smoker subjects will receive 1 PET scan with the radiotracer PHNO along with an amphetamine challenge and 1 mri .

Healthy smoker subjects will be asked to quit smoking for up to 8 weeks and will receive up to 2 PET scans with the radiotracer PHNO along with 2 amphetamine challenges and 2 mris over the course of their abstinence.

  • Trial with
    National Institute on Drug Abuse (NIDA)
  • Start Date
    09/19/2017
  • End Date
    09/29/2022
Trial Image

For more information about this study, contact:

Shannan Henry

I'm interested in volunteering

If you would prefer to contact a member of the Help us Discover team about this trial and other similar trials, please email helpusdiscover@yale.edu or call 877.978.8343

  • Last Updated
    11/29/2018
  • Study HIC
    #2000021470