Phase II Randomized Trial of Adjuvant Radiotherapy With or Without Cisplatin for p53 Mutated, Surgically Resected Squamous Cell Carcinoma of the Head and Neck (SCCHN)
Conditions
Larynx | Lip, Oral Cavity and Pharynx
Phase II
Volunteers
Health Professionals
What is the purpose of this trial?
This phase II trial studies how well radiation therapy with or without cisplatin works in treating patients with stage III-IV squamous cell carcinoma of the head and neck who have undergone surgery. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. It is not yet known if radiation therapy is more effective with or without cisplatin in treating patients with squamous cell carcinoma of the head and neck.
- Trial withEastern Coop Oncology Group-American College Radiology Imaging Network
- Start Date06/19/2016
- End Date12/30/2021
For more information about this study, contact:
Alexandra Minnella
I'm interested in volunteering
If you would prefer to contact a member of the Help us Discover team about this trial and other similar trials, please email helpusdiscover@yale.edu or call 877.978.8343
Principal Investigator
Sub-Investigators
- Aarti Bhatia, MD, MPH
- Abhijit Patel, MD, PhD
- Armand Russo, MD
- Benjamin Newton, MD
- David Witt, MD
- Greisy Fontal
- Hari Deshpande, MD
- Harold Tara Jr, MD
- Henry S. Park, MD, MPH
- Jane Kanowitz, MD
- Jason Haldas, MD
- Jeremy Kortmansky, MD
- Jerry Malefatto, MD
- Joseph N. Contessa, MD, PhD
- Justin Persico, MD
- Kay Haedicke, MD
- Lynsey Teulings
- Marianne Davies, NP
- Meena S. Moran, MD
- Melissa Young, MD, PhD
- Neal Fischbach, MD
- Roy H. Decker, MD/PhD
- Su Hsien Lim, MD
- Virginia Syombathy
- Wajih Kidwai, MD, FACP
- Last Updated07/13/2018
- Study HIC#1604017600