Phase II Randomized Trial of Adjuvant Radiotherapy With or Without Cisplatin for p53 Mutated, Surgically Resected Squamous Cell Carcinoma of the Head and Neck (SCCHN)
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Health Professionals
What is the purpose of this trial?
This phase II trial studies how well radiation therapy with or without cisplatin works in treating patients with stage III-IV squamous cell carcinoma of the head and neck who have undergone surgery. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. It is not yet known if radiation therapy is more effective with or without cisplatin in treating patients with squamous cell carcinoma of the head and neck.
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Principal Investigator
Sub-Investigators
- Aarti Bhatia, MD, MPH
- Abhijit Patel, MD, PhD
- Allison Campbell, MD, PhD
- Anca Bulgaru, MD
- Andrea Brennan
- Armand Russo, MD
- Benjamin Newton, MD
- Beverly Drucker, MD, PhD
- Bruce A. McGibbon, MD
- D. Barry Boyd, MD, MS
- David Witt, MD
- Elan Gorshein, DO, JD, MPH
- Francesca Montanari, MD
- Hari Deshpande, MD
- Harold Tara Jr, MD
- Henry S. Park, MD, MPH
- Jane Kanowitz, MD
- Jason Haldas, MD
- Jeremy Kortmansky, MD
- Kristen Hoxie
- Lynsey Teulings
- M. Sung Lee, MD
- Melissa Rasar Young, MD, PhD
- Michael Cohenuram, MD
- Neal Fischbach, MD
- Renee Moye
- Robert Legare, MD
- Sarah Carlson
- Stephanie Paine, APRN
- Stephen Lattanzi, MD
- Su Hsien Lim, MD
- Vanna Dest
- Virginia Syombathy
- Wajih Kidwai, MD, FACP
- Last Updated03/27/2024
- Study HIC#1604017600