Marriage of imaging and genetics opens new view of brain function
Neuroimaging has revolutionized the study of the brain, but can provide no information about what is actually happening at molecular level in humans. Scientists at Yale have developed new approaches to link gene expression patterns to brain signals captured by imaging.
Yale Cancer Researchers Suggest New Treatment for Rare Inherited Cancer
Studying two rare inherited cancer syndromes, Yale Cancer Center (YCC) scientists have found the cancers are driven by a breakdown in how cells repair their DNA. The discovery, published today in Nature Genetics, suggests a promising strategy for treatment with drugs recently approved for other forms of cancer.
Yale scientists apply new imaging tool to common brain disorders
A Yale-led team of researchers developed a new approach to scanning the brain for changes in synapses that are associated with common brain disorders. The technique may provide insights into the diagnosis and treatment of a broad range of disorders, including epilepsy and Alzheimer’s disease.
AI, radiologists match when it comes to classifying breast density
Dr. Liane Philpotts from Yale University presented her team's findings on Visage Imaging, Inc.'s Breast Density AI's agreement with radiologists on breast density classification at the 2023 ARRS annual meeting. The team found that the model showed over 99% agreement with radiologists of varying image reading volumes, indicating that it could be used in breast cancer screening as an adjunct or standalone assessment tool.Source: AuntMinnie.com
Low-Cost Low-Field MRI Has Arrived: What Does It Mean for Radiology?
A few years ago, one of our MRI technologists went into a supply closet in the neurosciences intensive care unit (NICU) and discovered a portable head-only 0.064-T MRI scanner that uses a resistive magnet powered by a standard power outlet.Source: Science Direct
The Yale Vascular Malformations Program (VaMP) identifies a culprit gene mutation implicated in the pathogenesis of "hepatic hemangiomas".
The Yale New Haven Hospital Vascular Malformations Program (VaMP), via a collaborative multidisciplinary effort, has identified somatic mosaic gene mutations (GJA4 encoding connexin 37) implicated in the pathogenesis of so-called “HEPATIC HEMANGIOMAS” in adult patients. This discovery questions the validity of the very term “hemangioma” in this particular anatomic distribution; and renders – for the first time - objective scientific support to the radiographically and clinically suspected notion that these lesions actually represent VENOUS MALFORMATIOMS - an entity with a completely different natural history, hemodynamics, angioarchitectural profile, and ergo therapeutic susceptibility.Source: Cutaneous and hepatic vascular lesions due to a recurrent somatic GJA4 mutation reveal a pathway for vascular malformation
Yale Faculty Pioneer Development and Testing of Portable MRI Device
Yale researchers have agreed to develop, deploy, and test a new portable MRI scanner, a device its developer hopes will cost a fraction of that of traditional MRIs and make the new imaging technology available in clinics in the U.S. and around the world.
Yale Radiology and Psychiatry Researchers Join with Penn Medicine to Create a New Center to Study Opioid Use Disorders
Opioid use disorder has reached epidemic levels in the United States. Over the last two decades, opioid-related overdose deaths increased by more than 50 percent, with nearly 50,000 in 2018, according to the Centers for Disease Control and Prevention. Researchers from Yale School of Medicine (YSM) and Penn Medicine, which comprises the Perelman School of Medicine at the University of Pennsylvania, have created a new center that focuses on neuroimaging to improve our understanding of opioid use disorders and find new treatments.
Study Reaches Multidisciplinary Consensus on Imaging for Kidney Stones
A multidisciplinary group of researchers conducted a systematic review of the scientific literature and engaged in a structured consensus process to determine scenarios where CT scans could be avoided in the diagnosis of renal colic.