Skip to Main Content

David N. Assis, MD

Associate Professor of Medicine; Director, Fellowship Program, Digestive Diseases

Contact Information

David N. Assis, MD

Patient Care Locations

Mailing Address

  • Digestive Diseases

    PO Box 208019

    New Haven, CT 06520-8019

    United States



Dr. Assis received his M.D. from Jefferson Medical College followed by internship and residency at Thomas Jefferson University Hospital in Philadelphia, where he was also Chief Resident. He completed training in gastroenterology and hepatology followed by transplant hepatology fellowships at Yale University.

His clinical and research interests are in autoimmune liver diseases. Specifically, he treats patients with autoimmune hepatitis, primary biliary cholangitis, and primary sclerosing cholangitis at his liver clinic. He also performs translational and basic research on autoimmune hepatitis using patient biospecimens in addition to work with animal models. He is investigating the link between the pro-inflammatory cytokine macrophage migration inhibitory factor (MIF) and autoimmune hepatitis, and the effect of psychological stress on autoimmune hepatitis.

In addition, Dr. Assis is an active member of the Adult Cystic Fibrosis Program at Yale. In this role, he evaluates and treats patients with Cystic Fibrosis who have GI or liver complications of their disease. He also consults on patients from outside Yale's Cystic Fibrosis program who have these complications.

Education & Training

  • Fellowship
    Yale University School of Medicine (2013)
  • Fellowship
    Yale University School of Medicine (2012)
  • Residency
    Thomas Jefferson University Hospital (2009)
  • Internship
    Thomas Jefferson University, Hospital (2006)
  • MD
    Jefferson Medical College (2005)
  • BS
    Messiah College (2001)


  • Roberts SJ,..., Assis DN. A small molecule inhibitor of Macrophage Migration Inhibitory Factor (MIF) significantly reduces liver injury in an antigen- and liver-specific pre-clinical model of autoimmune hepatitis (AIH). Abstract presented in oral format at the AASLD Liver Meeting. Oral Abstract #113
    Washington, United States 2017

Honors & Recognition

AwardAwarding OrganizationDate
Connecticut's Best Doctors 2019Connecticut Magazine2019

Professional Service

HepatologyAd hoc reviewer.2013 - Present

Departments & Organizations