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Ania Jastreboff, MD, PhD

Associate Professor; Director, Weight Management & Obesity Prevention; Medical Director, Yale Stress Center

Contact Information

Ania Jastreboff, MD, PhD

Patient Care Locations

Mailing Address

  • Endocrinology

    2 Church Street South

    New Haven, CT 06519

    United States

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Yale Medicine

Patient Care

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Appointments

Biography

Dr. Jastreboff is an Obesity Medicine physician-scientist, board certified in adult Endocrinology and Metabolism, Pediatric Endocrinology, and Obesity Medicine. She is nationally and internationally recognized in the Obesity Medicine field for developing Clinical Practice Guidelines (2016) for The Comprehensive Care of Patients with Obesity (AACE/ACE), serving on the Board of Directors for the American Board of Obesity Medicine (ABOM), educating the next generation of Obesity Medicine physicians by teaching annually at Harvard Blackburn Treating Obesity course and the Columbia/Cornell Obesity course, and conducting cutting-edge clinical translational obesity research. Her research includes both large, multi-center clinical outcomes trials using anti-obesity medication as well as neuroimaging studies (fMRI and PET) examining the neurobiology underlying obesity and the mechanisms of anti-obesity medications. Recently, Dr. Jastreboff served as the lead author on the SURMOUNT-1 trial investigating novel GIP/GLP-1 receptor agonist, tirzepatide, for the treatment of obesity (Jastreboff, et al., NEJM, 2022).

Clinically, Dr. Jastreboff specializes in sophisticated use of anti-obesity medication combinations to help patients reach their weight and health goals. She mainly sees patients for obesity treatment and weight management and additionally cares for patients with prediabetes and diabetes.

Dr. Jastreboff is board certified in Internal Medicine, Pediatrics, Endocrinology and Metabolism, Pediatric Endocrinology, and Obesity Medicine.

She completed her PhD at Yale University's Investigative Medicine Program focused on clinical translational investigation with a dissertation entitled “Neural Response to Food Cues and Stress in Individuals with Obesity".

Dr. Jastreboff's research is supported by NIH/NIDDK (R01s) and industry funded global, multi-center clinical trials.

Education & Training

  • Clinical Research Scholar
    Yale University School of Medicine (2013)
  • PhD
    Yale University Graduate School of Arts and Sciences (2011)
  • Endocrinology Postdoctoral Fellowship
    Yale University (2011)
  • Pediatric Endocrinology Postdoctoral Fellowship
    Yale University (2011)
  • Chief Resident
    University of Maryland (2006)
  • Residency
    University of Maryland School of Medicine (2006)
  • MD
    University of Maryland at Baltimore (2002)
  • BA
    Bucknell University, Art History (1998)

Activities

  • Pharmacotherapy for the treatment of adolescents with obesity
    Santiago, Chile 2020
  • Teenage Brains on Sugar: Neural Response to Monosaccharide Ingestion in Adolescent Obesity.
    Rio de Janeiro, Brazil 2020
  • Pharmacotherapy for the treatment of adolescent obesity: Where are we now? Where are we going?
    Rio de Janeiro, Brazil 2020
  • The best strategy for diabetes remission using obesity treatments is... pharmacotherapy
    Chicago, United States 2020
  • Overcoming barriers to use of anti-obesity pharmacotherapy
    Boston, United States 2020
  • Obesity Pharmacotherapy
    Boston, United States 2020
  • Pharmacological treatment of adolescents with obesity
    San Francisco, United States 2020
  • Pharmacotherapy for the treatment of adolescents with obesity: Where are we now? Where are we going?
    Worcester, United States 2020
  • Pharmacotherapy for the treatment of adolescents with obesity
    Cleveland, United States 2020
  • Obesity Pharmacotherapy Workshops and Meet the Expert
    Boston, United States 2020
  • Hold ‘em or Draw? Pharmacological Treatment on Adolescents with Obesity
    Las Vegas, United States 2019
  • Overcoming Barriers to use of Anti-Obesity Pharmacotherapy
    Boston, United States 2019
  • Obesity Pharmacotherapy
    Boston, United States 2019
  • Neuroimaging and Modulation in Obesity and Diabetes Research
    Bethesda, United States 2019
  • Teenage Brains on Sugar: Neural Response to Monosaccharide Ingestion in Adolescent Obesity
    New York, United States 2019
  • Obesity Pathophysiology: the role of the brain
    New York, United States 2019
  • Pharmacologic Treatment of Obesity
    Las Vegas, United States 2019
  • Treating patients with Diabetes and Obesity: the Role of Bariatric Surgery and Pharmacotherapy
    Ledyard, United States 2019
  • Obesity is Highly Prevalent Among Patients Admitted to an Emergency Department Chest Pain Observation Unit.
    Las Vegas, United States 2019
  • Obesity Is Highly Prevalent among Patients Admitted to an Emergency Department Chest Pain Observation Unit
    Las Vegas, United States 2019
  • Does Hyperinsulinemia in Obesity Elicit Brain Responses that Provoke Greater Motivation for Food?
    Bethesda, United States 2019
  • Obesity Is Associated with Reduced 11-beta-Hydoxysteroid Dehydrogenase Type I Levels in the Human Brain
    Bethesda, United States 2019
  • Investigating GLP-1 Agonism for Blocking Cocaine Euphoria and Self-Administration
    Orlando, United States 2019
  • Mindfulness based stress reduction for older couples with metabolic syndrome
    Vancouver, Canada 2019
  • Characterizing Obesity and Outcomes among Emergency Department Patients Admitted to a Chest Pain Observation Unit
    Worcester, United States 2019
  • Obesity Pharmacotherapy Workshops and Meet the Expert
    Boston, United States 2019
  • Pharmacologic Treatment of Obesity
    Phoenix, United States 2018
  • Obesity Pharmacotherapy Workshops and Meet the Expert
    Boston, United States 2018
  • Special Considerations in Use of Hybrid Closed Loop
    Charlotte, United States 2018
  • Obesity Physiology and Genetics
    Iowa City, United States 2018
  • Hyperinsulinemia Invokes Greater Cerebral Blood Flow in Reward and Motivation Regions in Obesity
    Orlando, United States 2018
  • Reduction of 11β-hydroxysteroid dehydrogenase type 1 enzyme levels with increasing body mass index: A Brain PET imaging study
    Philadelphia, United States 2018
  • Obesity is associated with reduced 11β-Hydroxysteroid Dehydrogenase Type 1 levels in the Human Brain
    Chicago, United States 2018
  • Severe Hypercalemia and acute pancreatitis in a postpartum woman
    Boston, United States 2018
  • Developing Precision Medicine Approaches to the Treatment of Severe Obesity in Adolescents
    Bethesda, United States 2017
  • Obesity Medicine: a new frontier
    Butler, United States 2017
  • Special Considerations in Use of Hybrid Closed Loop
    Fort Lauderdale, United States 2017
  • Obesity Pharmacotherapy Workshops
    Boston, United States 2017
  • Obesity Physiology and Genetics
    New York, United States 2017
  • Special Considerations in Use of Hybrid Closed Loop
    New Haven, United States 2017
  • Obesity Physiology and Genetics
    New York, United States 2017
  • Hedonic Eating/Food Reward and Appetite Regulation and the Development of Severe Obesity in Adolescents
    Bethesda, United States 2017
  • Does Hyperinsulinemia in Obesity Elicit Brain Responses that Provoke Greater Motivation for Food?
    San Diego, United States 2017
  • Preventing childhood obesity through a mindfulness-based parenting intervention for stress reduction
    Washington, United States 2017
  • Lower insulin sensitivity with increasing BMI is associated with greater high-calorie food intake
    Washington, United States 2017
  • The Polish Society of Endocrinology, 21st Congress
    Katowice, Poland 2016
  • 29th Annual Blackburn Course in Obesity Medicine
    Boston, United States 2016
    Case-based Workshops
  • Obesity Medicine Interhospital Rounds
    Boston, United States 2016
  • American Association of Clinical Endocrinologists (AACE) annual meeting
    Orlando, United States 2016
    AACE Comprehensive Clinical Practice Guidelines for the Medical Care of Patients with Obesity: An evidence-based approach to individualized medical management.
  • Preventing Childhood Obesity through a Family-Based Mindfulness Intervention
    Bethesda, United States 2016
  • Obesity Medicine: A New Frontier
    Albany, United States 2016
  • International Diabetes Federation
    Vancouver, Canada 2015
  • Relationship between insulin resistance, brain activity, and prospective weight gain
    Boston, United States 2015
  • Agonism for Blocking Cocaine Euphoria and Self-Administration
    Washington, United States 2015
  • NIH/NIDDK Intramural Program
    Bethesda, United States 2013
  • Response to Food Cues in Obese and Lean Adolescents
    Chicago, United States 2013
  • Neural Response to Food Cues and Stress in Obese Individuals
    Baltimore, United States 2010
  • Running: The Good, the Bad, and the Not So Ugly
    Baltimore, United States 2006
  • Pediatric Obesity in Old Order Amish
    Baltimore, United States 2006

Honors & Recognition

AwardAwarding OrganizationDate
Young Physician-Scientist AwardAmerican Association for Clinical Investigation (ASCI)2013
First Place Poster Award, Yale Multi-Disciplinary Endocrinology & Metabolism RetreatYale Univeristy2013
American Diabetes Association Young Investigator Travel Grant AwardAmerican Diabetes Association (ADA)2013
Burroughs Wellcome Fund Travel Award, Translational Science Meeting 2013Burroughs Wellcome Fund2013
Translational Science Poster Award Association for Clinical Research Training and Society for Clinical and Translational Science2013
Diabetes Endocrinology Research Center (DRC), Poster AwardeeYale University2011
Yale Pediatric Fellows’ Research Day, Oral presentation award winnerYale University2011

Professional Service

OrganizationRoleDate
WTNH (Channel 8)WTNH (Channel 8) On Call: Keto Diet – TV interview on news station: https://www.wtnh.com/news/health/news-8-on-call-keto-diet/2020
WTNH (Channel 8)WTNH (Channel 8). Top 3 dieting trends of 2020. Live TV interview on news station: https://www.wtnh.com/on-air/gmct-at-nine/top-3-dieting-trends-of-2020/2020
Better HealthBetter Health. 12 diets you should never try, according to health experts. https://www.eatthis.com/unhealthiest-diets-experts/2019
Better HealthBetter Health. Healthy gifts that are doctor recommended. https://www.eatthis.com/healthy-gifts/2019
WTNH (Channel 8)WTNH (Channel 8) On Call: New policy for children with severe obesity – TV interview on news station: https://www.wtnh.com/lifestyle/health-news/news-8-on-call-new-policy-for-children-with-severe-obesity/2019
Huffington PostHuffington Post. This is your body on Keto. https://www.huffpost.com/entry/keto-effects-body_l_5d9b58abe4b099389803e4412019
Health CentralHealth Central. When diet and exercise aren’t enough. https://www.healthcentral.com/article/obesity-treatments2019
WTNH (Channel 8)WTNH (Channel 8) Dealing with Diabetes on Campus – Live TV interview on news station: https://www.wtnh.com/on-air/dealing-with-diabetes-on-campus/2019
ADA (American Diabetes Association)Obesity/Pathogenesis of Obesity Subcommittee2019 - Present
NIHNIH Study Section ad hoc reviewer KNOD: Kidney, Nutrition, Obesity, and Diabetes2019
The Endocrine SocietyHormone Health Network (HHN) committee2019 - Present
NPRNational Public Radio (NPR) live interview on Where We Live with David Deroches and Lydia Brown: America’s Diet Craving. http://www.wnpr.org/post/americas-diet-craving2018
The Obesity SocietyClinical Committee2018 - Present
MedPage TodayMedPage Today: Progress in Type 2 Diabetes Care – interview (videos): (1) Treating the Root Cause: Obesity Medicine: https://www.medpagetoday.com/resource-centers/progress-in-type-2-diabetes-care/obesity-medicine/19 (2) How Effective is Weight Loss as Therapy for Type 2 Diabetes? https://www.medpagetoday.com/resource-centers/progress-in-type-2-diabetes-care/weight-loss-as-therapy-for-type-2-diabetes/3 (3) Diets in Diabetes: One Size Doesn’t Fit All: ): https://www.medpagetoday.com/resource-centers/progress-in-type-2-diabetes-care/diet-in-diabetes/22 (4) Beating the Set Point and Maintaining Weight Loss: https://www.medpagetoday.com/resource-centers/progress-in-type-2-diabetes-care/maintaining-weight-loss/20 (5) Potential Risks of Anti-obesity Medications in Patients with T2D: https://www.medpagetoday.com/resource-centers/progress-in-type-2-diabetes-care/potential-risks-of-anti-obesity-medications/212017
Department of Chronic Disease EpidemiologyFaculty Search Committee2017 - 2018
American Association of Clinical Endocrinology (AACE) and American College of EndocrinologyAACE 2nd Consensus Conference on Obesity Writing Task Force2017 - 2018
NIHNIH Study Section ad hoc reviewer PRDP: Psychosocial Risk and Disease Prevention2017
The Obesity SocietyGrant Reviewer (Scientific Review Committee)2017 - Present
The Obesity Societyco-chair neuroimaging program planning committee 2019-2020, committee member 2016-present2016 - 2020
Yale MedicineYale Medicine: Why Obesity is a Disease – interview (video) Obesity is a growing epidemic in America. Ania Jastreboff, MD, PhD discusses why obesity is a disease with biological underpinnings. In addition, she discusses treatment options and medications. https://www.yalemedicine.org/conditions/why-obesity-is-a-disease/2016
American Association of Clinical Endocrinology (AACE) and American College of EndocrinologyTask Force for the development of Clinical Practice Guidelines for the Comprehensive Medical Care of Patients with Obesity2015 - 2016
The Obesity SocietyObesity Medicine Fellowship Curriculum Development Committee2015 - 2016
The Obesity SocietyDevelopment of "Contributors to Obesity" infographic for organizational use and the Surgeon General (Committee)2015
American Association of Clinical Endocrinology (AACE) and American College of EndocrinologyTask Force for the Obesity Algorithm2015 - 2016

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