The Effect of Dietary Salt Intake on Immune Function in Patients With Multiple Sclerosis

What is the purpose of this trial?

The purpose of this work is to investigate the influence of dietary salt intake on immune function in multiple sclerosis (MS) subjects and healthy controls. This study primarily tests the hypothesis that higher dietary salt intake will be associated with a higher frequency of pathogenic Th17 cells and impaired function of protective regulatory T cells. If a relationship between dietary salt intake and immune function is observed, this study will also test: a) whether this relationship is unique to MS subjects or whether it is also present in healthy controls, and b) whether healthier immune function can be restored by restricting dietary salt intake.

Participation Guidelines

Ages: 18 - 60 years

Gender: Both


Start Date: 10/06/2015

End Date: 01/31/2019

Last Updated: 02/22/2018

Study HIC#: 1406014201

Get Involved

If you would prefer to contact a member of the Help us Discover team about this trial and other similar trials, please email or call 1-877-978-8348.

Trial Image


David A. Hafler

Principal Investigator