Pediatric Hepatic Malignancy International Therapeutic Trial (PHITT)

What is the purpose of this trial?

This partially randomized phase II/III trial studies how well cisplatin and combination chemotherapy works in treating children and young adults with hepatoblastoma or liver cancer after surgery. Drugs used in chemotherapy, such as cisplatin, doxorubicin, fluorouracil, vincristine sulfate, carboplatin, etoposide, irinotecan, sorafenib, gemcitabine and oxaliplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving combination chemotherapy after surgery may kill more tumor cells.



Children's Oncology Group (The)

Start Date: 05/24/2019

End Date: 03/31/2025

Last Updated: 05/28/2019

Study HIC#: 2000024256

Get Involved

For more information about this study, contact:
Sharon Huie
sharon.huie@yale.edu

If you would prefer to contact a member of the Help us Discover team about this trial and other similar trials, please email helpusdiscover@yale.edu or call 1-877-978-8348.

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