What is the purpose of this trial?
Although the efficacy of Cognitive Behavioral Therapy (CBT) has among the highest levels of empirical support for treatment of substance use disorders, its mechanisms of action have not been fully elucidated. However, it is known that regulation of craving is an important component of CBT, as well as of other types of treatment, including mindfulness-based treatments.The proposed study will investigate the regulation of craving as a putative mechanism of action of CBT, by (1) providing brief training in regulation of craving, and (2) experimentally manipulating the ¿type¿ of training in regulation of craving. We will then evaluate the effects of training on treatment outcome (e.g., drug taking) as well as on the neural correlates of craving and cognitive control of craving using functional magnetic resonance imaging (fMRI).
Ages: 18 - 60 years
National Institute on Drug Abuse
Start Date: 03/05/2013
End Date: 08/31/2019
Last Updated: 02/22/2018
Study HIC#: 1210010970