Investigating the Role of the Polyol Pathway in the Central Nervous System

What is the purpose of this trial?

The purpose of the study is to characterize CNS polyol pathway activity in lean, healthy individuals compared to obese individuals using

A) Brain MRS during hyperglycemic clamp and

B) analysis of metabolites in CSF obtained from lumbar puncture.


Participation Guidelines

Ages: 18 - 60 years

Gender: Both


Endocrine Fellows Foundation

Start Date: 01/01/2015

End Date: 11/01/2017

Last Updated: 02/22/2018

Study HIC#: 1408014461

Get Involved

For more information about this study, contact:
Mari-Lynet Knight
+1 203-737-4777
diabetes.research@yale.edu

If you would prefer to contact a member of the Help us Discover team about this trial and other similar trials, please email helpusdiscover@yale.edu or call 1-877-978-8348.

Trial Image