Active Surveillance of the Small Renal Mass

What is the purpose of this trial?

Primary Objectives/Endpoints:

  • Tumor growth rate in maximal dimension between CRG gene status, wild-type (M0) vs. mutant (M1) groups

Secondary Objectives/Endpoints:

  • To determine if established clear cell mRNA subtypes (A and B) are predictive of tumor growth rate or need for surgical intervention
  • To determine the association between CRG status surgical intervention (analysis by threshold and/or patient preference) between M0 and M1 groups To investigate if HIF2 or Ki-67 protein expression assessed by Automated Quantitative Analysis of immunohistochemistry are predictors of rapid tumor growth Comparison of Patient Anxiety Scores over time and correlation to tumor growth Determination of MRI imaging characteristics dynamic contrast enhancement and apparent diffusion coefficients are predictive of rapid tumor growth

Participation Guidelines

Ages: 18 years and older

Gender: Both

Yale University School of Medicine

Start Date: 07/28/2014

End Date: 08/01/2021

Last Updated: 06/22/2018

Study HIC#: 1312013110

Get Involved

For more information about this study, contact:
Neta Shanwetter Levit
+1 203-737-6247

If you would prefer to contact a member of the Help us Discover team about this trial and other similar trials, please email or call 1-877-978-8348.

Trial Image