The Gut-brain Axis: a Novel Target for Treating Behavioral Alterations in Obesity (CIDO OEA)

What is the purpose of this trial?

The aims of this project are to determine if dietary supplementation with NOPE-EGCG (PhosphoLeantm, 30mg NOPE+20mg EGCG per capsule) can:

  • rescue striatal function,
  • increase adherence to a diet,
  • reduce weight-gain after a diet,
  • improve performance on impulsivity, go/no-go tasks, and negative outcome learning, and
  • shift fat and sweet preference in overweight/obese human subjects in a double-blind cross-over design.

Participation Guidelines

Ages: 18 - 45 years

Gender: Both

National Cancer Institute

Start Date: 11/11/2013

End Date: 10/15/2017

Last Updated: 02/22/2018

Study HIC#: 1308012537

Get Involved

For more information about this study, contact:
Maria Hatungil
+1 203-562-9901

If you would prefer to contact a member of the Help us Discover team about this trial and other similar trials, please email or call 1-877-978-8348.

Trial Image


Dana Small

Principal Investigator