Combination Chemotherapy Before and After Surgery in Treating Patients With Localized Pancreatic Cancer

What is the purpose of this trial?

This phase II trial studies how well combination chemotherapy before and after surgery works in treating patients with localized pancreatic cancer. Drugs used in chemotherapy, such as leucovorin calcium, fluorouracil, irinotecan hydrochloride, and oxaliplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving combination chemotherapy before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed. Giving these treatments after surgery may kill any tumor cells that remain after surgery.


Participation Guidelines

Ages: 18 years and older

Gender: Both


Yale Cancer Center

Start Date: 09/18/2017

End Date: 12/31/2018

Last Updated: 06/22/2018

Study HIC#: 1306012255