Glutathione and the aging brain

What is the purpose of this trial?

This study is being done to examine the effect of aging on levels of glutathione (GSH), an antioxidant, in the brain.  

 The Specific Aims for this pilot study are: 1. To determine the feasibility of a study to quantify intracerebral levels of GSH as measured by 1H MRS at 4 Tesla in young and old individuals; 2. To begin defining the relationship between peripheral markers of metabolic status and intracerebral GSH; 3. To explore how aging alters the relationships between intracerebral GSH levels, human functional brain connectivity, and neurocognitive performance.


Participation Guidelines

Ages: 18 years and younger

Gender: Both


Yale Pepper Center

Start Date: 10/26/2017

End Date: 05/31/2020

Last Updated: 02/22/2018

Study HIC#: 2000021046

Get Involved

For more information about this study, contact:
Mari-Lynet Knight
mari-lynet.knight@yale.edu

If you would prefer to contact a member of the Help us Discover team about this trial and other similar trials, please email helpusdiscover@yale.edu or call 1-877-978-8348.

Trial Image