What is the purpose of this trial?
This is a randomized controlled trial of Cognitive Behavioral Therapy (CBT) versus Psychoeducation and Supportive Therapy (PST) in children with Autism Spectrum Disorder and moderate to severe anxiety. The study will utilize fMRI to identify CBT-invoked changes in levels of activity/functional connectivity within the neural circuits involved in emotion regulation and social perception. Matched typically developing children without autism and/or anxiety will be scanned twice, 16 weeks apart, to enable interpretation of treatment-evoked change relative to normative development. Read more about this study recently featured in a Yale Medicine article.
Ages: 8 - 14 years
Yale University School of Medicine
Start Date: 05/11/2016
End Date: 06/30/2020
Last Updated: 02/22/2018
Study HIC#: 1211011144