Pathogenesis of Youth and Type 2 Diabetes and Prediabetes

What is the purpose of this trial?

The goal is to explore if genetic factors are associated with insulin resistance in children and and adolescents. Screening includes having an oral glucose tolerance test to measure blood glucose levels and insulin levels and to have a blood sample drawn for genetic testing. Individuals with the CC or TT genotype of the TCF7L2 gene and are have impaired glucose tolerance based on the oral glucose tolerance test are eligible to participate in the main study which includes an infusion study and other tests of glucose and insulin secretion.

Participation Guidelines

Ages: 12 - 18 years

Gender: Both

Robert Leet and Clara Guthrie Patterson Trust

Start Date: 02/22/2017

End Date: 10/01/2022

Last Updated: 06/22/2018

Study HIC#: 2000020183

Get Involved

For more information about this study, contact:
Bridget Pierpont
+1 203-785-2942

If you would prefer to contact a member of the Help us Discover team about this trial and other similar trials, please email or call 1-877-978-8348.

Trial Image


Sonia Caprio

Principal Investigator