Characterization of Agrin/LRP4 Antibody Positive Myasthenia Gravis

What is the purpose of this trial?

Agrin and LRP4 antibodies have been detected in blood of MG patients. but a direct link with these antibodies and MG is not yet firmly established. The purpose of this study is to determine whether there is a relationship between Agrin and LRP4 antibodies in MG patients to their clinical features, disease severity, and how they have responded to treatments.

If you agree to participate in this study, the following procedures will occur: Review of your medical records, such as: MRI, EMG, X-Ray, CT Scan, current medications, treatments you have used to treat your MG; lumbar puncture; family history; breathing tests; blood draws; neurological exam; physical exam.


Participation Guidelines

Ages: 21 years and older

Gender: Both


Augusta University

Start Date: 08/11/2016

End Date: 04/01/2020

Last Updated: 02/22/2018

Study HIC#: 1603017470

Get Involved

For more information about this study, contact:
Joan Nye
+1 203-737-6886
joan.nye@yale.edu

If you would prefer to contact a member of the Help us Discover team about this trial and other similar trials, please email helpusdiscover@yale.edu or call 1-877-978-8348.

Trial Image

Investigators

Richard Nowak

Principal Investigator

Sub-Investigators