2008
Overexpression of UCP2 Protects Thalamic Neurons following Global Ischemia in the Mouse
Olsson T, Wieloch T, Diano S, Warden CH, Horvath TL, Mattiasson G. Overexpression of UCP2 Protects Thalamic Neurons following Global Ischemia in the Mouse. Cerebrovascular And Brain Metabolism Reviews 2008, 28: 1186-1195. PMID: 18301432, PMCID: PMC2642535, DOI: 10.1038/jcbfm.2008.8.Peer-Reviewed Original ResearchConceptsGlobal ischemiaHistologic damageNeurodegenerative diseasesDentate gyrus hippocampal subfieldGlobal brain ischemiaSelective neuronal deathWild-type littermatesDays of recoveryCell deathNeuronal damageOverexpression of UCP2Brain ischemiaHistopathological outcomeSublethal ischemiaThalamic neuronsNeuronal deathThalamic nucleiWT animalsThalamic regionsHippocampal subfieldsIschemiaExtensive cell deathUCP2 expressionThalamusLevels of UCP2
2003
Fasting Activates the Nonhuman Primate Hypocretin (Orexin) System and Its Postsynaptic Targets
Diano S, Horvath B, Urbanski HF, Sotonyi P, Horvath TL. Fasting Activates the Nonhuman Primate Hypocretin (Orexin) System and Its Postsynaptic Targets. Endocrinology 2003, 144: 3774-3778. PMID: 12933647, DOI: 10.1210/en.2003-0274.Peer-Reviewed Original ResearchConceptsPerifornical regionArcuate nucleusHypothalamic regulationC-Fos-expressing cellsLateral hypothalamic cellsC-fosMedial preoptic areaVariety of endocrineC-fos expressionDiverse brain regionsHCRT axonsLeptin levelsNuclear c-FosDorsomedial hypothalamusAsymmetric synapsesBasal forebrainPresent studyPostsynaptic targetsDorsomedial nucleusNeuropeptide Y.Preoptic areaThalamic nucleiHcrt neuronsHcrt systemAxon terminals