2005
Estrogen enhances light‐induced activation of dorsal raphe serotonergic neurons
Abizaid A, Mezei G, Thanarajasingam G, Horvath TL. Estrogen enhances light‐induced activation of dorsal raphe serotonergic neurons. European Journal Of Neuroscience 2005, 21: 1536-1546. PMID: 15845081, DOI: 10.1111/j.1460-9568.2005.03964.x.Peer-Reviewed Original ResearchConceptsOvariectomized ratsRaphe nucleusDorsal raphe serotonergic neuronsEstradiol-treated ovariectomized ratsAbility of estradiolDouble-labeled cellsFos-immunoreactive cellsRaphe serotonergic neuronsMedian raphe nucleusFos-positive nucleiRaphe nuclei regionMidbrain rapheSerotonin immunocytochemistryOvarian functionSerotonergic neuronsEstrogen treatmentFos immunoreactivitySerotonergic systemFood intakeNeuronal responsesDirect projectionsPhotic stimulationEstradiolEstrogenNormal onset
2002
Uncoupling protein 2 (UCP2) lowers alcohol sensitivity and pain threshold
Horvath B, Spies C, Horvath G, Kox WJ, Miyamoto S, Barry S, Warden CH, Bechmann I, Diano S, Heemskerk J, Horvath TL. Uncoupling protein 2 (UCP2) lowers alcohol sensitivity and pain threshold. Biochemical Pharmacology 2002, 64: 369-374. PMID: 12147287, DOI: 10.1016/s0006-2952(02)01167-x.Peer-Reviewed Original ResearchConceptsCentral nervous systemTemperature sensationNervous systemBasal forebrain areasMajor risk factorAcute ethanol exposureAcute alcohol consumptionImpairment of painPeripheral energy expenditureAbuse of ethanolProtein 2Ethanol-induced toleranceWild-type animalsUCP2 knockoutPain thresholdTime of recoveryInduces toleranceRisk factorsEthanol exposureForebrain areasAxon terminalsNeuronal responsesAcute exposureAlcohol consumptionEnergy homeostasis