2010
Fgfr2 Is Required for the Development of the Medial Prefrontal Cortex and Its Connections with Limbic Circuits
Stevens HE, Smith KM, Maragnoli ME, Fagel D, Borok E, Shanabrough M, Horvath TL, Vaccarino FM. Fgfr2 Is Required for the Development of the Medial Prefrontal Cortex and Its Connections with Limbic Circuits. Journal Of Neuroscience 2010, 30: 5590-5602. PMID: 20410112, PMCID: PMC2868832, DOI: 10.1523/jneurosci.5837-09.2010.Peer-Reviewed Original ResearchConceptsMedial prefrontal cortexCerebral cortexFibroblast growth factor receptorCKO miceExcitatory neuronsPrefrontal cortexCortical neuron developmentEntire cerebral cortexRadial glial cellsSpecific fibroblast growth factor receptorsGrowth factor receptorGABAergic neuronsLimbic circuitsCortical neuronsGlial cellsSubcortical stationsBed nucleusCortical developmentLimbic systemStria terminalisSynaptic terminalsSecondary decreaseNeuronal precursorsVentricular zoneNeuron development
1997
Aromatase in axonal processes of early postnatal hypothalamic and limbic areas including the cingulate cortex
Horvath T, Roa-Pena L, Jakab R, Simpson E, Naftolin F. Aromatase in axonal processes of early postnatal hypothalamic and limbic areas including the cingulate cortex. The Journal Of Steroid Biochemistry And Molecular Biology 1997, 61: 349-357. PMID: 9365210, DOI: 10.1016/s0960-0760(97)80032-5.Peer-Reviewed Original ResearchConceptsAxonal processesLimbic areasStria terminalisCritical perinatal periodMedial preoptic areaPostnatal day 5Limbic cortexArcuate nucleusHypothalamic areaNeuronal perikaryaLimbic structuresMedial septumPerinatal periodPreoptic areaDiagonal bandMedial nucleusAxon terminalsImmunoreactive elementsPerikaryal labelingPeriventricular regionLateral septumBed nucleusParacrine actionRat brainLateral habenulaGonadal steroids target AMPA glutamate receptor-containing neurons in the rat hypothalamus, septum and amygdala: a morphological and biochemical study.
Diano S, Naftolin F, Horvath T. Gonadal steroids target AMPA glutamate receptor-containing neurons in the rat hypothalamus, septum and amygdala: a morphological and biochemical study. Endocrinology 1997, 138: 778-89. PMID: 9003015, DOI: 10.1210/endo.138.2.4937.Peer-Reviewed Original ResearchConceptsGonadal steroidsHypothalamic regionsExcitatory neurotransmissionAMPA receptorsReceptor-containing neuronsAMPA receptor expressionLevels of GluR1GluR2/3 expressionHormonal milieuHypothalamic areaFemale ratsAndrogen receptorDouble immunocytochemistryEstradiol treatmentHypothalamic functionReceptor expressionGlutamate receptorsEstrogen receptorBed nucleusHormonal treatmentRat hypothalamusHigh incidenceStimulatory influenceWestern blotHypothalamus