Yale Researchers Take Stem Cells One Step Closer to Replacing Parathyroid Gland Function
Yale investigators have developed a multistep process that models the biological instructions to create parathyroid gland cells from pluripotent stem cells, a significant milestone along the path toward helping people who lack the hormones released by parathyroid glands.
Study points to potential personalized approach to treating lupus
In individuals with lupus, immune cells attack the body’s own tissue and organs as if they are enemy invaders. A new Yale-led study describes how a protein found in common bacteria triggers that auto-immune response. The finding opens the door to future therapies targeting the bacteria rather than the immune system, the researchers said.
Yale Stem Cell Center will host two-day symposium to celebrate its 10th anniversary
Since it was founded in 2006, the Yale Stem Cell Center has supported the ground-breaking work of researchers and scientists working in basic stem cell research and translational science. On Thursday, Nov. 10, and Friday, Nov. 11, the center will hold a symposium in honor of its 10th anniversary.
Failure of cells’ ‘garbage disposal’ system may contribute to Alzheimer’s
Lysosomes, the “garbage disposal” systems of cells, are found in great abundance near the amyloid plaques in the brain that are a hallmark of Alzheimer’s disease. Scientists have long assumed that their presence was helpful — that they were degrading the toxic proteins that trigger amyloid plaque formation.
Get to know the speaker of our Cell Biology Seminar series! An interview with Dr. Sara Wickström (MD PhD)
Exciting, interesting cutting edge science talks are featured in our seminar series! Along with the scientific story that has to be told, there is also the story of our great guest speakers! How did it start? How is it going? Follow our series on “Get to know the Speaker!” The first speaker was Dr. S. Wickström (MD PhD) from the University of Helsinki.
Simple Change to Microscope Opens Up a Complex Panorama of Cells
Yale researchers in the lab of Joerg Bewersdorf have developed a way to visualize extremely tiny structures by using standard light microscopy, a world previously only accessible by expensive and cumbersome electron microscopy.Source: YaleNews
Position Openings in the Zhang lab
The Zhang lab at the Department of Cell Biology, Yale University, uses single-molecule approaches, especially high-resolution optical tweezers, to study folding dynamics of proteins involved in fundamental biological processes and human diseases. The lab is now seeking graduate students and postdocs for research in the following three areas: • Regulated SNARE folding and assembly. • Membrane protein folding, stability, and protein-membrane interactions. • Instrumental development. Prior research experience in single-molecule biophysics is not required. However, postdoc candidates should have strong quantitative skills and solid training in biophysics, molecular biology, or physics. If you are interested in these positions, please contact Dr. Yongli Zhang at email@example.com.
Scientists find many gene 'drivers' of cancer, but warn: Don't ignore 'passengers'
A massive analysis of the entire genomes of 2,658 people with 38 different types of cancer has identified mutations in 179 genes and gene regulators as “drivers” — variations in DNA sequences that lead to the development of cancer.
In the right (lab) culture, mentorship flourishes — and science benefits
You might imagine a science lab looking a bit sterile and impersonal — little sunlight, masked figures in white coats pouring neon-colored liquid into beakers, all business. You might not expect to hear a science lab referred to as familial, where badminton tournaments, movie nights and barbeques are commonplace.
Colón-Ramos named McConnell Duberg Associate Professor
Daniel A. Colón-Ramos, PhD, recently appointed as Dorys McConnell Duberg Associate Professor of Neuroscience and Cell Biology, focuses his research on how synapses are formed and maintained to control behavior and store memories. Colón-Ramos’ discoveries have altered long-held views on the process and may offer important clues in the fight against disease.
Study Explores Role of Metabolism in Immune Cell Behavior
What makes healthy cells change and become dysfunctional to the point of causing disease? In addition to a disruption in genes that regulate cells, there is another factor in cell misbehavior that involves metabolism, say Yale researchers.