Fighting Breast and Ovarian Cancer With a Lupus Antibody
After discovering a specific lupus antibody that can penetrate cancer cells and, with a grant from Women's Health Research at Yale, showing it makes cancer cells vulnerable to standard treatments, Dr. Peter Glazer and his colleagues are moving a treatment to clinical trials.
Sex Differences in Gastrointestinal Cancer
With this year's Wendy U. and Thomas C. Naratil Pioneer Award and co-funding from the Yale Cancer Center, Dr. Pamela Kunz is conducting one of the first studies to examine sex differences in treating neuroendocrine neoplasms (NENs), a rare form of cancer often found in the gastrointestinal tract.
Using Particles That Are Smaller Than the Head of a Pin to Treat Cancer
Thanks in part to research begun more than a decade ago with funding from Women’s Health Research at Yale, Dr. W. Mark Saltzman is working with colleagues on a way to deploy effective cancer-fighting medication safely with the help of nanoparticles.
Treatment with Genetically Altered Viruses Targets and Destroys Ovarian Cancer in Mice
Researchers have successfully eliminated chemotherapy-resistant ovarian cancer cells in mice using a single injection of two viruses genetically combined and altered to be safe, leading to long-term survival and demonstrating a potential breakthrough treatment for women.
WHRY Funds Studies on Stroke, Endometrial Cancer, and Addiction to Opioids
Women’s Health Research at Yale today announced funding for three studies investigating sex differences in stroke, endometrial cancer, and alternate pain relief for women recovering from past opioid use who are giving birth via cesarean section.
Deadlier Colon Cancer Develops Differently in Women and Men
WHRY-affiliated researchers have found that colon cancer tumor cells produce energy for growth differently in women and men, and that this difference is associated with a more aggressive form of tumor growth with a higher incidence in women.
HEALTH NOTES: Black and Hispanic Cancer Patients Are Underrepresented in Clinical Trials
A new study has shown that clinical trials for new cancer medications rarely analyze data on safety and effectiveness by race and that black and Hispanic patients are consistently underrepresented among participants.
More women in U.S. receive 3-D mammography but disparities remain
Use of 3-D mammography, an advanced form of breast cancer screening, has risen rapidly in recent years, according to Yale Cancer Center researchers in a new study. But adoption of the technology varies widely, reflecting emerging disparities in care, they said.
HEALTH NOTES: Aggressive Uterine Cancer Rates Are Rising in the U.S., Especially for Minority Women
Women in the United States have experienced a steep rise in rates of aggressive uterine cancer since 2000, an upward trend that has been particularly steep for minority women, according to a new study.
Alessandro Santin Recognized as 2019 ASCO Leader in Cancer Care
Research by Alessandro Santin, M.D., professor of gynecology, obstetrics & reproductive sciences and leader of the Disease Aligned Research Team of the Gynecologic Oncology Program at Smilow Cancer Hospital and Yale Cancer Center, has had his research selected as one of the top five advances of the year by the American Society of Clinical Oncology (ASCO).
Yale Study Identifies How Cancer Drug Inhibits DNA Repair in Cancer Cells
Yale Cancer Center researchers have found that a cancer drug thought to be of limited use possesses an unforeseen property. It is able to stop certain cancer cells from repairing their DNA in order to survive. The study suggests that combining this drug, cediranib, with other agents could potentially deliver a lethal blow in cancer that uses a specific process to create DNA repair cells.
Yale Cancer Center researchers find genetic explanations behind the rapid spread of ovarian cancer
In a breakthrough study, Yale Cancer Center (YCC) researchers have defined the genetic characteristics of primary, metastatic and recurrent ovarian tumors and evaluated new targeted therapies to treat the disease. The findings are reported today in the Proceedings of the National Academy of Science (PNAS) online early edition.
Breaking it Down: How the Chemistry of Digestion is Uncovering Sex-Specific Causes of Colon Cancer
A new technology called metabolomics allows researchers to explore the small chemicals formed and used during digestion as a window into the formation of diseases such as colon cancer, seeking early warning signs and potent tactics for prevention.