2022
Prior differences in previous trauma exposure primarily drive the observed racial/ethnic differences in posttrauma depression and anxiety following a recent trauma
Harnett N, Dumornay N, Delity M, Sanchez L, Mohiuddin K, Musey P, Seamon M, McLean S, Kessler R, Koenen K, Beaudoin F, Lebois L, van Rooij S, Sampson N, Michopoulos V, Maples-Keller J, Haran J, Storrow A, Lewandowski C, Hendry P, Sheikh S, Jones C, Punches B, Kurz M, Swor R, McGrath M, Hudak L, Pascual J, House S, An X, Stevens J, Neylan T, Jovanovic T, Linnstaedt S, Germine L, Datner E, Chang A, Pearson C, Peak D, Merchant R, Domeier R, Rathlev N, O'Neil B, Sergot P, Bruce S, Miller M, Pietrzak R, Joormann J, Barch D, Pizzagalli D, Sheridan J, Smoller J, Luna B, Harte S, Elliott J, Ressler K. Prior differences in previous trauma exposure primarily drive the observed racial/ethnic differences in posttrauma depression and anxiety following a recent trauma. Psychological Medicine 2022, 53: 2553-2562. PMID: 35094717, PMCID: PMC9339026, DOI: 10.1017/s0033291721004475.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderPrevious trauma exposureTrauma exposurePosttraumatic depressionPrior differencesChildhood emotional abusePrior trauma exposureSelf-report assessmentsWhite participantsPosttraumatic stressStress disorderAnxiety symptomsEmotional abuseLife stressorsPTSD ratesEarly aftermathPosttraumatic dysfunctionAnxietySymptom trajectoriesRecent traumaEthnic differencesAURORA studyParticipantsSymptom recoveryRecent research
2015
Amyloid-β, Anxiety, and Cognitive Decline in Preclinical Alzheimer Disease: A Multicenter, Prospective Cohort Study
Pietrzak RH, Lim YY, Neumeister A, Ames D, Ellis KA, Harrington K, Lautenschlager NT, Restrepo C, Martins RN, Masters CL, Villemagne VL, Rowe CC, Maruff P. Amyloid-β, Anxiety, and Cognitive Decline in Preclinical Alzheimer Disease: A Multicenter, Prospective Cohort Study. JAMA Psychiatry 2015, 72: 284-291. PMID: 25629787, DOI: 10.1001/jamapsychiatry.2014.2476.Peer-Reviewed Original ResearchConceptsPreclinical Alzheimer's diseaseSubjective memory complaintsElevated anxiety symptomsVerbal memoryExecutive functionGlobal cognitionAnxiety symptomsCognitive declineCognitive changesMemory complaintsAβ statusDepressive symptomsLow anxiety groupComprehensive neuropsychological evaluationHigh anxiety groupRole of anxietyFlorbetapir F 18Visual memoryCognitive domainsVisuospatial abilitiesMild cognitive impairmentNeuropsychological evaluationCognitive functionProspective cohort studyMore rapid decline