Nasal Vaccination May Protect Against Respiratory Viruses Better Than Injected Vaccines
Akiko Iwasaki, PhD, discusses her lab's finding that intranasal vaccinations, by triggering immune properties of mucosal membranes, may offer better protection against respiratory viruses than injected vaccines.
Nasal Vaccine May Aid Fight Against New Viral Variants
Akiko Iwasaki and her colleagues found that intranasal vaccination provided broad-based protection against heterologous respiratory viruses in mice, while so-called systemic immunization, which uses an injection to elicit body-wide protection, did not.Source: YaleNews
Iwasaki Is Honored by the International Cytokine & Interferon Society
Akiko Iwasaki, PhD, Waldemar Von Zedtwitz Profesor of Immunobiology and Molecular, Cellular, and Developmental Biology; and professor of dermatology, is a 2019 recipient of the Seymour & Vivian Milstein Award for Excellence in Interferon and Cytokine Research, given by the International Cytokine & Interferon Society (ICIS).
Antiretroviral Therapy Crucial in Preventing non-Hodgkin Lymphoma, YSPH Study Reinforces
A research team led by the Yale School of Public Health has found that for people living with HIV/AIDS, both recent immunosuppression and prolonged HIV viremia play important and independent roles in the development of non-Hodgkin lymphoma.
Study reveals new way to ‘rewire’ immune cells to slow tumor growth
Inside a tumor, immune cells and cancer cells battle for survival. The advantage may go to the cells that metabolize the most glucose, say Yale researchers who have identified a new way to boost immune response by metabolically “rewiring” immune cells.
The Immune System and its Frontier Defense Against Herpes
"In August, associate research scientist Norifumi Iijima, Ph.D and Yale Professor of Immunobiology Akiko Iwasaki published a study providing evidence that a network of immune cells residing in the mucosa of the mouse vagina is required for full protection from lethal infection."Source: Yale Scientific
Research in the News: Combination therapies combat HIV at cell junctions, Yale researchers find
A new Yale University study indicates that cell-to-cell transmission of HIV particles contributes to the development of full-blown AIDS and helps predict which anti-retroviral therapies will be most effective at keeping the disease at bay.
Yale Study Seeks to Understand Neurobiology Underlying Bipolar Disorder Vs. Major Depressive Disorder
Yale scientists, including Sophie Holmes, PhD; Ruth Asch, PhD; and Irina Esterlis, PhD, used positron emission tomography to understand the neurobiology underlying bipolar disorder versus major depressive disorder. The findings were published in Biological Psychiatry.Source: Biological Psychiatry
Collaboration on NIH grant between Sullivan, Nez Henderson will create program to help Indigenous women experiencing domestic violence quit smoking
Tami Sullivan, PhD, associate professor of psychiatry at Yale School of Medicine, and Patricia Nez Henderson, MD, MPH, vice president for the Black Hills Center for American Indian Health (BHCAIH) and the first Indigenous woman to graduate from Yale School of Medicine, have been awarded a grant from the National Institutes of Health (NIH) to pilot a mindfulness-based, culturally-tailored smoking cessation intervention for Indigenous women who experience intimate partner violence (IPV).
A Randomized Clinical Trial to Evaluate an Atrial Fibrillation Stroke Prevention Shared Decision‐Making Pathway
Oral anticoagulation (OAC) reduces stroke and disability in atrial fibrillation (AF) but is underutilized. Researchers, including Julio Nunes, MD, first-year resident, evaluated the effects of a novel patient‐clinician shared decision‐making (SDM) tool in reducing OAC patient's decisional conflict as compared to usual care.Source: Journal of the American Heart Association
Does Street Outreach Engage Its Intended Target Population? Clinical Experience in the Veteran’s Health Administration Homeless Service Programs
Emma Lo, MD; Jack Tsai, PhD; Elina Stefanovics, PhD; and Robert Rosenheck, MD, are co-authors of a paper in Psychiatric Quarterly that found veterans engaged through clinical street outreach programs reported substantially more days of unsheltered homelessness than a clinic-referred group of veterans.Source: Psychiatric Quarterly