DELIVER: Dapagliflozin cuts risk for worsening HF in adults with, without type 2 diabetes
Dapagliflozin reduces risk for worsening heart failure and cardiovascular death in adults with heart failure with mildly reduced or preserved ejection fraction, regardless of baseline HbA1c, according to findings from the DELIVER trial.Source: Healio
High liver fat associated with impaired glucose, type 2 diabetes in pediatric obesity
Children with obesity and a high level of liver fat content are more likely to have impaired glucose tolerance, prediabetes and type 2 diabetes compared with those with normal liver fat content, according to Sonia Caprio, MD.Source: Healio
WHRY Launches Studies on Endometrial Cancer, Addiction to Opioids, and Stroke
While continuing to focus on the impacts of COVID-19, the center has enlarged its research portfolio to include new projects on the prevention of endometrial cancer in a growing cohort of women at high risk, non-opioid pain management following a cesarean section for women with opioid use disorder who are in recovery, and sex differences in stroke.
WHRY Funds Studies on Stroke, Endometrial Cancer, and Addiction to Opioids
Women’s Health Research at Yale today announced funding for three studies investigating sex differences in stroke, endometrial cancer, and alternate pain relief for women recovering from past opioid use who are giving birth via cesarean section.
Endocrine Society Educates Congress About the Science of PFAS Exposure
The Endocrine Society hosted a congressional briefing on November 6th, 2019, on the latest science with policy makers on how federally funded research is helping to understand and address the health effects of exposure to per- and polyfluoroalkyl substances, also known as PFAS. Expert scientists gathered to discuss widespread contamination issues and diverse health effects attributed to PFAS exposure. Zeyan Liew, PhD, MPH, from the Yale School of Public Health shared his research exploring the effects of PFAS on maternal thyroid function and neurodevelopmental outcomes in exposed children.Source: Endocrine News
MFS2 Regulation Controls Phosphate Excretion, Renal Stone Formation, Study Finds
A high phosphate diet caused stones within the Malpighian renal tubules and resulted in reduced lifespan of fruit flies, says new study led by Yale School of Medicine’s Clemens Bergwitz, MD, associate professor of medicine (endocrinology).
Yale Expert Testifies in Washington on the Harm Caused by Soaring Insulin Prices
On April 2, Kasia Lipska, MD, MPH, assistant professor of medicine (endocrinology), testified in Washington before the House Committee on Energy & Commerce Oversight and Investigations Subcommittee on the severe harm that high insulin prices does to patients, including her own.
Clinical Research Forum Chooses Carpenter's Work as One of the Year's Top Ten Research Achievements
The Clinical Research Forum has presented its 2019 Top Ten Clinical Research Achievement Awards, which include work by Thomas O. Carpenter, MD, professor of pediatrics (endocrinology) and of orthopaedics and rehabilitation, and clinical professor of nursing.
Chelsea Clinton, author Randi Epstein discuss ‘hormones, heroes, hucksters’
“Medicine and health sciences don’t exist in isolation from their broader social, cultural, and political contexts,” said Chelsea Clinton, vice chair of the Clinton Foundation, and adjunct assistant professor at the Columbia University Mailman School of Public Health, to Dr. Randi Hutter Epstein, the writer-in-residence for the Yale Program for Humanities in Medicine.Source: YaleNews
Leptin hormone spurs body’s shift from burning carbs to fat
To keep the human brain supplied with energy when food was scarce, mammals evolved the ability to switch from burning carbohydrates to burning fat in order to preserve skeletal muscle that would otherwise be metabolized and converted to glucose. Scientists have long believed that the transition to fat metabolism was instigated solely by a drop in insulin. But a new study has identified leptin — a hormone made by fat cells — as a key mediator in this fundamental biological process.