2020
A general-purpose Monte Carlo particle transport code based on inverse transform sampling for radiotherapy dose calculation
Liang Y, Muhammad W, Hart GR, Nartowt BJ, Chen ZJ, Yu JB, Roberts KB, Duncan JS, Deng J. A general-purpose Monte Carlo particle transport code based on inverse transform sampling for radiotherapy dose calculation. Scientific Reports 2020, 10: 9808. PMID: 32555530, PMCID: PMC7300009, DOI: 10.1038/s41598-020-66844-7.Peer-Reviewed Original ResearchConceptsPhoton transportBoundary crossing algorithmMonte Carlo particle transport codeMonte Carlo methodTransport simulationsAcceptance-rejection samplingRadiotherapy dose calculationsPhoto-electric effectParticle transport codeEGSnrc simulationsCarlo methodBremsstrahlung eventsInelastic scatteringPair productionRayleigh scatteringThread divergenceMC simulationsTransport codeMC codeHistory schemeParticle transportCrossing algorithmInverseElectron transportSimulation accuracy
2015
Concomitant Imaging Dose and Cancer Risk in Image Guided Thoracic Radiation Therapy
Zhang Y, Wu H, Chen Z, Knisely JP, Nath R, Feng Z, Bao S, Deng J. Concomitant Imaging Dose and Cancer Risk in Image Guided Thoracic Radiation Therapy. International Journal Of Radiation Oncology • Biology • Physics 2015, 93: 523-531. PMID: 26460994, DOI: 10.1016/j.ijrobp.2015.06.034.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAgedAged, 80 and overAorta, ThoracicBody SizeBreastChildChild, PreschoolCone-Beam Computed TomographyFemaleHeartHumansLungMaleMiddle AgedMonte Carlo MethodOrgans at RiskPhantoms, ImagingPhotonsPrecision MedicineProtonsRadiation DosageRadiography, ThoracicRadiotherapy, Image-GuidedRisk AssessmentSex FactorsSpinal CordThoracic WallThoraxConceptsConcomitant imaging doseThoracic radiation therapyCancer riskRadiation therapyMean dosesCardiac substructuresKilovoltage cone-beamImaging doseAdverse eventsPediatric patientsMedian dosesCancer patientsRight ventricleExtra radiation doseSpinal cordHigh dosesPatientsCone beamPlanning CT imagesChest dimensionsDosesPatient sizeImaging guidanceTherapyDoseDosimetric comparison of two arc-based stereotactic body radiotherapy techniques for early-stage lung cancer.
Liu H, Ye J, Kim JJ, Deng J, Kaur MS, Chen ZJ. Dosimetric comparison of two arc-based stereotactic body radiotherapy techniques for early-stage lung cancer. Medical Dosimetry : Official Journal Of The American Association Of Medical Dosimetrists 2015, 40: 76-81. PMID: 25499078, DOI: 10.1016/j.meddos.2014.10.004.Peer-Reviewed Original Research
2014
Personalized Quantification of Imaging Doses to Children and Adults Scanned by Standard Thoracic Cone Beam CT in Radiation Therapy
Zhang Y, Wu H, Chen Z, Knisely J, Nath R, Yue H, Feng Z, Bao S, Deng J. Personalized Quantification of Imaging Doses to Children and Adults Scanned by Standard Thoracic Cone Beam CT in Radiation Therapy. International Journal Of Radiation Oncology • Biology • Physics 2014, 90: s76. DOI: 10.1016/j.ijrobp.2014.05.453.Peer-Reviewed Original Research
2013
Monte Carlo Estimation of Dose to the Cardiac Implantable Electronic Devices From a kVCBCT System Used in Image Guided Radiation Therapy
Ming X, Feng Y, Chen Z, Zhang Y, Nath R, Deng J. Monte Carlo Estimation of Dose to the Cardiac Implantable Electronic Devices From a kVCBCT System Used in Image Guided Radiation Therapy. International Journal Of Radiation Oncology • Biology • Physics 2013, 87: s152. DOI: 10.1016/j.ijrobp.2013.06.393.Peer-Reviewed Original ResearchDosimetric Impact of Treatment Couch on Volumetric Modulated Arc Therapy (VMAT)
Ye J, Liu H, Kim J, Deng J, Chen Z. Dosimetric Impact of Treatment Couch on Volumetric Modulated Arc Therapy (VMAT). International Journal Of Radiation Oncology • Biology • Physics 2013, 87: s708-s709. DOI: 10.1016/j.ijrobp.2013.06.1877.Peer-Reviewed Original Research
2012
Kilo-Voltage Imaging Doses to Organs-at-Risk in CBCT-guided Breast Radiation Therapy
Deng J, Chen Z, Knisely J, Nath R. Kilo-Voltage Imaging Doses to Organs-at-Risk in CBCT-guided Breast Radiation Therapy. International Journal Of Radiation Oncology • Biology • Physics 2012, 84: s233-s234. DOI: 10.1016/j.ijrobp.2012.07.606.Peer-Reviewed Original ResearchSU‐E‐T‐289: On the Use of a Diode Array for the Commissioning of Dynamically‐Wedged Asymmetric Fields Generated by Varian EDW's in the Pinnacle Treatment Planning System
Ahmad M, Liu W, Deng J, Nguyen K, Wu D, Chen Z, Moran M, Nath R. SU‐E‐T‐289: On the Use of a Diode Array for the Commissioning of Dynamically‐Wedged Asymmetric Fields Generated by Varian EDW's in the Pinnacle Treatment Planning System. Medical Physics 2012, 39: 3770-3770. PMID: 28517261, DOI: 10.1118/1.4735357.Peer-Reviewed Original ResearchArray systemMonte Carlo code BEAMnrcEnhanced dynamic wedgeDiode arrayCylindrical chamberSolid waterDose profilesCentral axisVirtual waterAcceptable accuracyPinnacle3 treatment planning systemBeamDiode array systemOutput factorsWedge angleSegmented treatment tablesAsymmetric fieldsSimulationsConvolution calculationMC predictionWater phantomWaterAxis dose profilesCentral axis percentage depth dosesPercentage depth doses
2011
Quality Assurance Comparison of Intensity Modulated Stereotactic Radiosurgery between Different Treatment Planning Systems
Guo F, Carlson D, Chen Z, Deng J, Picone J, Nath R. Quality Assurance Comparison of Intensity Modulated Stereotactic Radiosurgery between Different Treatment Planning Systems. International Journal Of Radiation Oncology • Biology • Physics 2011, 81: s867. DOI: 10.1016/j.ijrobp.2011.06.1545.Peer-Reviewed Original ResearchSU‐E‐T‐485: Clinical Evaluation of Inverse Planning Models and IMRT Delivery Systems in the Framework of AAPM TG‐119 Protocol
Ahmad M, Liu W, Lund M, Moran M, Richards P, Wu D, Chen Z, Deng J, Nath R. SU‐E‐T‐485: Clinical Evaluation of Inverse Planning Models and IMRT Delivery Systems in the Framework of AAPM TG‐119 Protocol. Medical Physics 2011, 38: 3600-3600. DOI: 10.1118/1.3612438.Peer-Reviewed Original ResearchTesticular Doses in Image-Guided Radiotherapy of Prostate Cancer
Deng J, Chen Z, Yu JB, Roberts KB, Peschel RE, Nath R. Testicular Doses in Image-Guided Radiotherapy of Prostate Cancer. International Journal Of Radiation Oncology • Biology • Physics 2011, 82: e39-e47. PMID: 21489702, DOI: 10.1016/j.ijrobp.2011.01.071.Peer-Reviewed Original ResearchConceptsImage-guided radiotherapyTesticular dosesFull-fan modeProstate cancerFemoral headLess doseCBCT scansHalf-fan modeProstate cancer patientsKilovoltage cone-beamCancer patientsIntensity-modulated radiotherapy (IMRT) treatmentKilovoltage CBCTSuperior-inferior directionCone beamDosesCBCT fieldProstate patientsRectumDoseProstateMore doseRadiotherapy treatmentPatientsRadiotherapyKilovoltage Imaging Doses in the Radiotherapy of Pediatric Cancer Patients
Deng J, Chen Z, Roberts KB, Nath R. Kilovoltage Imaging Doses in the Radiotherapy of Pediatric Cancer Patients. International Journal Of Radiation Oncology • Biology • Physics 2011, 82: 1680-1688. PMID: 21477943, DOI: 10.1016/j.ijrobp.2011.01.062.Peer-Reviewed Original ResearchConceptsPediatric cancer patientsCancer patientsTesticular shieldingSpinal cordKilovoltage cone-beamCBCT dosesMean dosesClinical conditionsDose reductionLarge dosesFemoral headPatientsCBCT scansCone beamDosesFull-fan modeOptical nerveCBCT fieldCordDose increaseImaging dosesScanning protocolOARsRadiotherapyHalf-fan mode
2010
Impact of Kilo-voltage Imaging Doses to the Radiotherapy of Pediatric Cancer Patients
Deng J, Chen Z, Roberts K, Nath R. Impact of Kilo-voltage Imaging Doses to the Radiotherapy of Pediatric Cancer Patients. International Journal Of Radiation Oncology • Biology • Physics 2010, 78: s590-s591. DOI: 10.1016/j.ijrobp.2010.07.1377.Peer-Reviewed Original Research
2009
A Serial-imaging Based 4D Dose Computation System for Prostate Implant Dosimetry
Chen Z, Deng J, Carlson D, Roberts K, Decker R, Rockwell S, Nath R. A Serial-imaging Based 4D Dose Computation System for Prostate Implant Dosimetry. International Journal Of Radiation Oncology • Biology • Physics 2009, 75: s349. DOI: 10.1016/j.ijrobp.2009.07.800.Peer-Reviewed Original ResearchMonte Carlo Investigation of Stereotactic Radiosurgery of Spinal Metastases
Deng J, Chen Z, Knisely J, Decker R, Chiang V, Nath R. Monte Carlo Investigation of Stereotactic Radiosurgery of Spinal Metastases. IFMBE Proceedings 2009, 25/1: 13-16. DOI: 10.1007/978-3-642-03474-9_4.Peer-Reviewed Original ResearchSpinal metastasesStereotactic radiosurgeryDose-volume histogramsMean doseAnalytical anisotropic algorithmRisk of recurrenceTarget dose coverageDose distributionPencil beam convolutionSpinal cordDose coverageTarget dosePTV doseTreatment planMetastasisHomogeneity indexDoseRadiosurgeryPBC resultsPatientsTreatment planning systemPatient anatomyCommercial treatment planning systemDose discrepanciesAccurate dose distributionImpact of Kilo-Voltage Cone Beam Computed Tomography on Image-Guided Radiotherapy of Prostate Cancer
Deng J, Chen Z, Nath R. Impact of Kilo-Voltage Cone Beam Computed Tomography on Image-Guided Radiotherapy of Prostate Cancer. IFMBE Proceedings 2009, 25/1: 17-20. DOI: 10.1007/978-3-642-03474-9_5.Peer-Reviewed Original ResearchKilo-voltage cone beamProstate cancerImage-guided radiotherapyDosevolume histogramsExcessive dosesCone beamFemur headAdjacent critical structuresPatient anatomyTesticular doseCBCT dosesTesticular dosesImage-guided radiation therapyRadiation therapyMost dosesSuperior-inferior directionDVH analysisCritical organsCancerDosesIGRT treatmentReal patient anatomyDosimetric impactScanning protocolPosterior side
2008
Clinical implementation of enhanced dynamic wedges into the Pinnacle treatment planning system: Monte Carlo validation and patient-specific QA
Ahmad M, Deng J, Lund MW, Chen Z, Kimmett J, Moran MS, Nath R. Clinical implementation of enhanced dynamic wedges into the Pinnacle treatment planning system: Monte Carlo validation and patient-specific QA. Physics In Medicine And Biology 2008, 54: 447-465. PMID: 19098353, DOI: 10.1088/0031-9155/54/2/018.Peer-Reviewed Original Research
2007
On the Need to Compensate for Edema-Induced Dose Reductions in Preplanned 131Cs Prostate Brachytherapy
Chen ZJ, Deng J, Roberts K, Nath R. On the Need to Compensate for Edema-Induced Dose Reductions in Preplanned 131Cs Prostate Brachytherapy. International Journal Of Radiation Oncology • Biology • Physics 2007, 70: 303-310. PMID: 17980500, PMCID: PMC2289996, DOI: 10.1016/j.ijrobp.2007.09.007.Peer-Reviewed Original ResearchConceptsDose reductionProstate brachytherapyDose compensationLarge edemaBiochemical recurrence-free survivalRecurrence-free survivalSignificant dose reductionEffects of edemaSublethal damage repairAdditional irradiationPrescription doseProstate cancerIndividual patientsEdemaEdema evolutionPrescribed doseProstate edemaEffective doseRadiobiologic effectsBrachytherapyDoseProstate implantsDose responseImplantsA Two-Stage IMRT Treatment Protocol Provides More Robust Radiotherapy for Prostate Cancer in Presence of Inter- and Intra-Fractional Organ Motions
Chen Z, Deng J, Nath R, Peschel R. A Two-Stage IMRT Treatment Protocol Provides More Robust Radiotherapy for Prostate Cancer in Presence of Inter- and Intra-Fractional Organ Motions. International Journal Of Radiation Oncology • Biology • Physics 2007, 69: s713-s714. DOI: 10.1016/j.ijrobp.2007.07.2100.Peer-Reviewed Original ResearchA Monte Carlo Assisted Research and Treatment Planning System
Deng J, Yan Y, Chen Z, Weng X, Nath R. A Monte Carlo Assisted Research and Treatment Planning System. International Journal Of Radiation Oncology • Biology • Physics 2007, 69: s636-s637. DOI: 10.1016/j.ijrobp.2007.07.1972.Peer-Reviewed Original Research