2016
Energy Modulated Photon Radiotherapy: A Monte Carlo Feasibility Study
Zhang Y, Feng Y, Ming X, Deng J. Energy Modulated Photon Radiotherapy: A Monte Carlo Feasibility Study. BioMed Research International 2016, 2016: 7319843. PMID: 26977413, PMCID: PMC4763028, DOI: 10.1155/2016/7319843.Peer-Reviewed Original ResearchConceptsIMRT plansPediatric brain tumorsNovel treatment modalitiesNormal tissue sparingDifferent tumor sitesDosimetric gainLung cancerTreatment modalitiesIndividual patientsBrain tumorsTissue sparingIMRT techniqueTumor sitePersonalized carePhoton radiotherapyThyroid lesionsDose distributionIntegral doseRadiotherapy treatmentInverse planning systemPatientsRadiotherapyFeasibility studyModern radiotherapy treatmentsClinical IMRT plans
2015
Concomitant Imaging Dose and Cancer Risk in Image Guided Thoracic Radiation Therapy
Zhang Y, Wu H, Chen Z, Knisely JP, Nath R, Feng Z, Bao S, Deng J. Concomitant Imaging Dose and Cancer Risk in Image Guided Thoracic Radiation Therapy. International Journal Of Radiation Oncology • Biology • Physics 2015, 93: 523-531. PMID: 26460994, DOI: 10.1016/j.ijrobp.2015.06.034.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAgedAged, 80 and overAorta, ThoracicBody SizeBreastChildChild, PreschoolCone-Beam Computed TomographyFemaleHeartHumansLungMaleMiddle AgedMonte Carlo MethodOrgans at RiskPhantoms, ImagingPhotonsPrecision MedicineProtonsRadiation DosageRadiography, ThoracicRadiotherapy, Image-GuidedRisk AssessmentSex FactorsSpinal CordThoracic WallThoraxConceptsConcomitant imaging doseThoracic radiation therapyCancer riskRadiation therapyMean dosesCardiac substructuresKilovoltage cone-beamImaging doseAdverse eventsPediatric patientsMedian dosesCancer patientsRight ventricleExtra radiation doseSpinal cordHigh dosesPatientsCone beamPlanning CT imagesChest dimensionsDosesPatient sizeImaging guidanceTherapyDose
2006
Evaluation of the EDR-2 film for relative dosimetry of high-energy photon and electron beams
Ahmad M, Chen Z, Song H, Deng J, Nath R. Evaluation of the EDR-2 film for relative dosimetry of high-energy photon and electron beams. Radiation Protection Dosimetry 2006, 120: 159-162. PMID: 16644932, DOI: 10.1093/rpd/ncj006.Peer-Reviewed Original ResearchConceptsEDR-2 filmsElectron beamRelative dosimetryHigh-energy photonsClinical radiation dosimetryDose profilesPhotonsRadiation dosimetryBeamDose distributionRadiographic filmsSensitometric studyFilmsDosimetryTreatment planning techniquesElectronsDiodesSymmetryKVFlatnessPlanning techniquesDistribution
2004
Modelling 6 MV photon beams of a stereotactic radiosurgery system for Monte Carlo treatment planning
Deng J, Guerrero T, Ma C, Nath R. Modelling 6 MV photon beams of a stereotactic radiosurgery system for Monte Carlo treatment planning. Physics In Medicine And Biology 2004, 49: 1689-1704. PMID: 15152924, DOI: 10.1088/0031-9155/49/9/007.Peer-Reviewed Original ResearchConceptsMV photon beamMonte Carlo treatmentPhoton beamsPhase spaceEGS4/BEAM systemPercent depth dose curvesParticle phase spaceMonte Carlo treatment planningDepth dose curvesFull phase spaceDose calculationsStereotactic radiosurgery systemContaminant electronsCircular planar sourceMonte Carlo systemPrimary photonsMultiple source modelDose profilesSecondary collimatorDose curvesTotal maximum doseDose contributionBeamBeam systemOriginal phase space
2003
Commissioning 6 MV photon beams of a stereotactic radiosurgery system for Monte Carlo treatment planning
Deng J, Ma C, Hai J, Nath R. Commissioning 6 MV photon beams of a stereotactic radiosurgery system for Monte Carlo treatment planning. Medical Physics 2003, 30: 3124-3134. PMID: 14713079, DOI: 10.1118/1.1624753.Peer-Reviewed Original ResearchConceptsMonte Carlo dose calculationsMonte Carlo treatment planningBeam phase spaceOutput factorsCentral axis depth dose curvesDose profilesMonte Carlo treatmentMeasurement dataMultiple source modelCyberknife stereotactic radiosurgery systemPhase spaceMV photon beamDepth dose curvesDose calculationsSource modelStereotactic radiosurgery systemFluence distributionStandard measurement dataSource distributionPhoton beamsAxis distanceEnergy spectrumCollimator sizeDose curvesAveraging effectA comparative dosimetric study on tangential photon beams, intensity-modulated radiation therapy (IMRT) and modulated electron radiotherapy (MERT) for breast cancer treatment
Ma C, Ding M, Li JS, Lee MC, Pawlicki T, Deng J. A comparative dosimetric study on tangential photon beams, intensity-modulated radiation therapy (IMRT) and modulated electron radiotherapy (MERT) for breast cancer treatment. Physics In Medicine And Biology 2003, 48: 909-924. PMID: 12701895, DOI: 10.1088/0031-9155/48/7/308.Peer-Reviewed Original ResearchConceptsIntensity-modulated radiation therapyTangential photon beamsContralateral breastBreast cancerRadiation therapyTreatment planMaximum doseBreast cancer treatmentTreatment optimizationComparative dosimetric studyBreast treatment plansPhoton treatment plansPhoton beamsElectron radiotherapySuperficial targetsMultiple beam anglesLungMedium dosesDose conformityTangential beamsNormal tissuesCancer treatmentMERT plansIMRT plansMV photon beam
2001
Derivation of electron and photon energy spectra from electron beam central axis depth dose curves
Deng J, Jiang S, Pawlicki T, Li J, Ma C. Derivation of electron and photon energy spectra from electron beam central axis depth dose curves. Physics In Medicine And Biology 2001, 46: 1429-1449. PMID: 11384063, DOI: 10.1088/0031-9155/46/5/308.Peer-Reviewed Original ResearchConceptsPhoton energy spectrumDepth dose curvesCentral axis depth dose curvesPhase-space simulationsElectron beamEnergy spectrumDose curvesElectron beam dose calculationsLinear accelerator treatment headCentral axis percentage depth-dose (PDD) curvesPercentage depth dose curvesDerivation of electronPhase space dataClinical electron beamsMeV electron beamSpace simulationTreatment headPDD curvesDose profilesElectronsBeamCorresponding spectraPhotonsDose calculationsSpectraThe MLC tongue-and-groove effect on IMRT dose distributions
Deng J, Pawlicki T, Chen Y, Li J, Jiang S, Ma C. The MLC tongue-and-groove effect on IMRT dose distributions. Physics In Medicine And Biology 2001, 46: 1039-1060. PMID: 11324950, DOI: 10.1088/0031-9155/46/4/310.Peer-Reviewed Original Research
2000
Energy- and intensity-modulated electron beams for radiotherapy
Ma C, Pawlicki T, Lee MC, Jiang SB, Li JS, Deng J, Yi B, Mok E, Boyer AL. Energy- and intensity-modulated electron beams for radiotherapy. Physics In Medicine And Biology 2000, 45: 2293-2311. PMID: 10958195, DOI: 10.1088/0031-9155/45/8/316.Peer-Reviewed Original ResearchConceptsModulated electron radiotherapyIntensity-modulated electron beamElectron beamMultileaf collimatorElectron beam energyInter-leaf leakageDose distributionElectron intraMonte Carlo dose calculationsPencil beam algorithmLeaf endsBeam energyPhoton beamsElectron radiotherapyOblique incidencePatient surfaceMonte Carlo methodBeamBeam algorithmField shapeMonte Carlo simulationsDose calculationsSuperficial targetsCarlo methodCarlo simulationsPhoton beam characterization and modelling for Monte Carlo treatment planning
Deng J, Jiang S, Kapur A, Li J, Pawlicki T, Ma C. Photon beam characterization and modelling for Monte Carlo treatment planning. Physics In Medicine And Biology 2000, 45: 411-427. PMID: 10701512, DOI: 10.1088/0031-9155/45/2/311.Peer-Reviewed Original ResearchConceptsOriginal phase spacePhase spaceMonte Carlo calculationsPhoton jawsCarlo calculationsMonte Carlo treatment planningSource-surface distanceVarian Clinac 2100CPhase space filesPrimary collimatorMultiple source modelPhoton beamsPlanar fluenceAngular distributionsMV photon beamClinac 2100CField sizeSource modelBeam characterizationDose distributionHeterogeneous phantomsGood agreementBeam characteristicsFlattening filterEnergy spectrum