2024
Impact of setup errors on the robustness of linac‐based single‐isocenter coplanar and non‐coplanar VMAT plans for multiple brain metastases
Sun X, Guan F, Yun Q, Jennings M, Biggs S, Wang Z, Wang W, Zhang T, Shi M, Zhao L. Impact of setup errors on the robustness of linac‐based single‐isocenter coplanar and non‐coplanar VMAT plans for multiple brain metastases. Journal Of Applied Clinical Medical Physics 2024, 25: e14317. PMID: 38439583, PMCID: PMC11244668, DOI: 10.1002/acm2.14317.Peer-Reviewed Original ResearchNon-coplanar plansPlanning target volumeGross tumor volumePatient setup errorsPlan evaluation metricsSetup errorsMultiple brain metastasesImpact of setup errorsNon-coplanar VMAT plansDose delivery accuracyGamma passing ratesRobust treatment plansModified plansSingle-isocenterVMAT plansGamma analysisRotation errorBrain metastasesDose coverageLinac-basedTreatment planningDelivery accuracyTarget volumePrescribed doseNon-coplanar
2019
Potential for Improvements in Robustness and Optimality of Intensity-Modulated Proton Therapy for Lung Cancer with 4-Dimensional Robust Optimization
Ge S, Wang X, Liao Z, Zhang L, Sahoo N, Yang J, Guan F, Mohan R. Potential for Improvements in Robustness and Optimality of Intensity-Modulated Proton Therapy for Lung Cancer with 4-Dimensional Robust Optimization. Cancers 2019, 11: 35. PMID: 30609652, PMCID: PMC6356681, DOI: 10.3390/cancers11010035.Peer-Reviewed Original ResearchLung cancer patientsIntensity-modulated proton therapyCancer patientsIMPT dose distributionsClinical target volume coverageNormal tissue dose distributionsTarget volume coveragePlanning target volumeTarget dose coverageConventional planning target volumeRespiratory motionDose distributionDifferent tumor sizesTarget dose distributionProton therapyTumor sizeLung cancerDose coverageTreatment planIMPT plansTarget volumeNormal tissuesVolume coverageRespiratory phasesPatients
2018
Patterns of Local-Regional Failure After Intensity Modulated Radiation Therapy or Passive Scattering Proton Therapy With Concurrent Chemotherapy for Non-Small Cell Lung Cancer
Yang P, Xu T, Gomez DR, Deng W, Wei X, Elhalawani H, Jin H, Guan F, Mirkovic D, Xu Y, Mohan R, Liao Z. Patterns of Local-Regional Failure After Intensity Modulated Radiation Therapy or Passive Scattering Proton Therapy With Concurrent Chemotherapy for Non-Small Cell Lung Cancer. International Journal Of Radiation Oncology • Biology • Physics 2018, 103: 123-131. PMID: 30165127, DOI: 10.1016/j.ijrobp.2018.08.031.Peer-Reviewed Original ResearchConceptsNon-small cell lung cancerInternal target volumePlanning target volumeCell lung cancerLarge tumorsRegional failureMarginal failureLocal failureLung cancerSmall tumorsCox proportional hazards analysisTarget volumeLocal-regional failureOnly independent predictorOverall survival rateProportional hazards analysisProton therapyComputed tomography simulationPassive Scattering Proton TherapyConcurrent chemotherapyLocoregional failureFavorable survivalIndependent predictorsTumor controlTomography scan