Multi-omics approaches for biomarker discovery in predicting the response of esophageal cancer to neoadjuvant therapy: A multidimensional perspective
Yang Z, Guan F, Bronk L, Zhao L. Multi-omics approaches for biomarker discovery in predicting the response of esophageal cancer to neoadjuvant therapy: A multidimensional perspective. Pharmacology & Therapeutics 2024, 254: 108591. PMID: 38286161, DOI: 10.1016/j.pharmthera.2024.108591.Peer-Reviewed Original ResearchConceptsPathological complete responseNeoadjuvant chemoradiotherapyEsophageal cancerLocally advanced esophageal cancerPathological complete response patientsAdvanced esophageal cancerStandard treatment strategyPredicting treatment responsePredicting nCRT responseMulti-omics dataMulti-omicsComplete responseNeoadjuvant therapyChemoradiation responseNCRT responsePredictive biomarkersSurvival outcomesActive surveillanceTreatment responsePlanned surgeryEC patientsTreatment strategiesMulti-omics approachImproved biomarkersOrgan preservation