2025
Prediction Model for Safe Contrast Volume Thresholds to Prevent Postcontrast Acute Kidney Injury after Endovascular Abdominal Aortic Aneurysm Repair
Bader J, Li Y, Lee C, Li J, Said S, Slade M, Huang Y, Kuwayama D, Guzman R, Ochoa Chaar C. Prediction Model for Safe Contrast Volume Thresholds to Prevent Postcontrast Acute Kidney Injury after Endovascular Abdominal Aortic Aneurysm Repair. Journal Of Vascular Surgery 2025 PMID: 40490161, DOI: 10.1016/j.jvs.2025.05.041.Peer-Reviewed Original ResearchElective endovascular abdominal aortic aneurysm repairEndovascular abdominal aortic aneurysm repairRisk of PC-AKIAbdominal aortic aneurysm repairMultivariate logistic regression analysisAortic aneurysm repairPC-AKIAcute kidney injuryLogistic regression analysisPerioperative mortalityAneurysm repairKidney injuryComplication of endovascular abdominal aortic aneurysm repairPatient characteristicsIncidence of preoperative comorbiditiesPost-contrast acute kidney injuryPostcontrast acute kidney injuryAssociated with development of chronic kidney diseaseAssociated with perioperative mortalityDevelopment of chronic kidney diseaseVascular Quality Initiative databasePreoperative patient characteristicsKaplan-Meier analysisProlonged hospital stayRenal artery stentingSex Differences in Perioperative Complications of Lower Extremity Revascularization for Peripheral Artery Disease
Terrazos-Moreno R, Vu A, Alameddine D, Zhuo H, Mena-Hurtado C, Mojibian H, Guzman R, Ochoa Chaar C. Sex Differences in Perioperative Complications of Lower Extremity Revascularization for Peripheral Artery Disease. Annals Of Vascular Surgery 2025, 121: 113-119. PMID: 40447038, DOI: 10.1016/j.avsg.2025.05.041.Peer-Reviewed Original ResearchLower extremity revascularizationPeripheral arterial diseaseArtery diseaseEndovascular lower extremity revascularizationPerioperative complicationsExtremity revascularizationChronic renal insufficiencyOutcomes of patientsRetrospective chart reviewOutcomes of lower extremity revascularizationCoronary artery diseaseRisk of early thrombosisLower-extremity revascularizationRenal insufficiencyTertiary centerInitial presentationWound infectionIncreased bleedingNo significant differenceSmoking historyProcedure typePAD patientsPatient characteristicsPerioperative periodIncreased riskThe Incidence and Significance of Delayed Bleeding Events After Lower Extremity Revascularization in Patients with Advanced Peripheral Arterial Disease
Hundito A, Wells N, Tuttle M, Alameddine D, Huttler J, Slade M, Strosberg D, Lee A, Guzman R, Ochoa Chaar C. The Incidence and Significance of Delayed Bleeding Events After Lower Extremity Revascularization in Patients with Advanced Peripheral Arterial Disease. Journal Of Vascular Surgery 2025 PMID: 40187383, DOI: 10.1016/j.jvs.2025.03.394.Peer-Reviewed Original ResearchLower extremity revascularizationPeripheral arterial diseaseBleeding eventsBleeding episodesAdvanced peripheral arterial diseaseArtery diseaseAntithrombotic therapyExtremity revascularizationRetrospective review of patientsIncidence of bleeding eventsAssociated with worse overall outcomesDelayed bleeding eventsDiscontinuation of ASAPrescription of antithrombotic therapyRecurrent bleeding episodesReview of patientsChronic renal insufficiencyEnd-stage renal diseaseOutcomes of patientsTertiary care centerHistory of smokingRecurrent bleeding eventsLong-term outcomesCoronary artery diseaseLower-extremity revascularizationVariations in Antithrombotic Prescriptions and Evaluation of Extended Clopidogrel Therapy After Lower Extremity Revascularization for Peripheral Artery Disease
Wells N, Alameddine D, Dhanda U, Tran L, Silva D, Slade M, Guzman R, Ochoa Chaar C. Variations in Antithrombotic Prescriptions and Evaluation of Extended Clopidogrel Therapy After Lower Extremity Revascularization for Peripheral Artery Disease. Journal Of Vascular Surgery 2025 PMID: 40122313, DOI: 10.1016/j.jvs.2025.03.183.Peer-Reviewed Original ResearchLower extremity revascularizationPeripheral arterial diseaseDuration of clopidogrel therapyClopidogrel therapyAntithrombotic prescriptionAntithrombotic combinationsAntithrombotic therapyExtremity revascularizationArtery diseasePatients treated with clopidogrelAssociated with improved survivalClinical characteristics of patientsMedical records of patientsLong-term follow-upChronic renal insufficiencyMACE-free survivalAssociated with bleedingElectronic medical records of patientsAdverse cardiac eventsKaplan-Meier curvesRecords of patientsTertiary care centerCongestive heart failureLong-term outcomesComparison of patientsOutcomes of mechanical thrombectomy for acute limb ischemia at a tertiary referral center
Loh S, Nasir A, Strosberg D, Ochoa Chaar C, Guzman R, Tonnessen B. Outcomes of mechanical thrombectomy for acute limb ischemia at a tertiary referral center. Journal Of Vascular Surgery 2025, 82: 205-215.e2. PMID: 40024380, DOI: 10.1016/j.jvs.2025.02.027.Peer-Reviewed Original ResearchTertiary referral centerAcute limb ischemiaAdverse cardiovascular eventsReferral centerMechanical thrombectomyOpen surgeryThirty-dayCardiovascular eventsConversion to open surgeryLimb ischemiaTreated with mechanical thrombectomyMedian follow-upCatheter-directed thrombolysisManagement of acute limb ischemiaDuration of symptomsThirty-day complicationsOutcomes of mechanical thrombectomyRisk of limb lossHigh risk of limb lossAcute limb ischemia casesMechanical thrombectomy devicesBleeding eventsMulticenter trialThrombosed bypassesThrombosed stent
2024
The association of reduced ejection fraction with the outcomes of endovascular abdominal aortic aneurysm repair
Bellamkonda K, Zogg C, Desai N, Strosberg D, Stone D, Guzman R, Ochoa Chaar C. The association of reduced ejection fraction with the outcomes of endovascular abdominal aortic aneurysm repair. Journal Of Vascular Surgery 2024, 81: 866-876. PMID: 39725244, DOI: 10.1016/j.jvs.2024.12.039.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic Aneurysm, AbdominalBlood Vessel Prosthesis ImplantationCardiomyopathiesDatabases, FactualEndovascular ProceduresFemaleHumansMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesRisk AssessmentRisk FactorsStroke VolumeTime FactorsTreatment OutcomeUnited StatesVentricular Function, LeftConceptsEndovascular aneurysm repairEjection fractionReduced EFIschemic cardiomyopathyNormal EFNonischemic cardiomyopathyAneurysm repairOutcomes of endovascular abdominal aortic aneurysm repairOutcomes of endovascular aneurysm repairEndovascular abdominal aortic aneurysm repairAssociated with higher 30-day mortalitySymptomatic abdominal aortic aneurysmElective endovascular aneurysm repairAbdominal aortic aneurysm repairHigher 30-day mortalityVascular Quality Initiative databaseAssociated with high mortalityAortic aneurysm repairVascular Surgery guidelinesAbdominal aortic aneurysmLong-term mortalityVascular Quality InitiativeSeverity of cardiomyopathyReduction of EFSurgery guidelinesOpen and endovascular treatment of the common femoral artery in a tertiary care center
Wells N, Hundito A, Tuttle M, Alameddine D, Aboian E, Arhuidese I, Fischer U, Perez Lozada J, Guzman R, Ochoa Chaar C. Open and endovascular treatment of the common femoral artery in a tertiary care center. Journal Of Vascular Surgery 2024, 81: 386-396.e2. PMID: 39442735, PMCID: PMC11748354, DOI: 10.1016/j.jvs.2024.10.027.Peer-Reviewed Original ResearchLower extremity revascularizationTreated with open surgeryPeripheral arterial diseaseCFA endarterectomyEndovascular therapyOpen surgeryEndovascular treatmentEndovascular lower extremity revascularizationTreated with endovascular therapyCompared to open surgeryAssociated with higher perioperative complicationsLower extremity revascularization proceduresPost-operative bleedingFemoral arteryImprove patient selectionKaplan-Meier analysisTertiary care centerTertiary-care centerLong-term outcomesEndovascular treatment of peripheral arterial diseaseLonger hospital lengthMALE-free survivalMultivariate logistic regressionTreatment of peripheral arterial diseaseCommon femoral arteryRuptured Complex Aortoiliac Aneurysm in an Elderly Patient With a Kidney Transplant Presenting With Sciatica
Kostiuk V, Rodriguez P, Aboian E, Kuwayama D, Guzman R, Chaar C. Ruptured Complex Aortoiliac Aneurysm in an Elderly Patient With a Kidney Transplant Presenting With Sciatica. Vascular And Endovascular Surgery 2024, 59: 411-415. PMID: 39438778, DOI: 10.1177/15385744241296220.Peer-Reviewed Original ResearchCommon iliac artery aneurysmsIliac artery aneurysmsAbdominal aortic aneurysmArtery aneurysmRenal artery originsKidney transplantationAortic aneurysmEndovascular repairAneurysm repairArtery originLeft common iliac artery aneurysmConcomitant abdominal aortic aneurysmNon-contrast CT scanComplex aneurysm anatomyComplex aortoiliac aneurysmsIntra-abdominal aneurysmsFemoral-femoral bypassRinged PTFE graftEndovascular aneurysm repairKidney transplant functionFunctioning kidney transplantExternal iliac arteryRisk of ruptureSciatica symptomsAortoiliac aneurysmsThe Incidence and Impact of Cardiac Function Decline after Lower Extremity Revascularization
Jamil Y, Huttler J, Alameddine D, Wu Z, Mena-Hurtado C, Velazquez E, Guzman R, Ochoa Chaar C. The Incidence and Impact of Cardiac Function Decline after Lower Extremity Revascularization. Annals Of Vascular Surgery 2024, 110: 414-423. PMID: 39343374, DOI: 10.1016/j.avsg.2024.07.119.Peer-Reviewed Original ResearchCardiac functional declineStable cardiac functionLower extremity revascularizationPeripheral arterial diseaseCardiac functionFollow-upExtremity revascularizationFunctional declineElectronic records of patientsKaplan-Meier analysisRecords of patientsMode of revascularizationAdverse limb eventsLower-extremity revascularizationTransthoracic echocardiogramReintervention rateHeart failureDiabetes mellitusPeriprocedural bleedingPatient characteristicsArtery diseasePatientsLimb eventsIncreased mortalityRevascularizationThe radiographic relationship of the femoral head, inguinal ligament, and common femoral artery bifurcation for optimal vascular access
Brahmandam A, Huttler J, Bellamkonda K, Setia O, Cardella J, Stewart W, Guzman R, Ochoa Chaar C. The radiographic relationship of the femoral head, inguinal ligament, and common femoral artery bifurcation for optimal vascular access. Journal Of Vascular Surgery 2024, 80: a21-a22. DOI: 10.1016/j.jvs.2024.07.019.Peer-Reviewed Original ResearchThe Degree of Inferior Vena Cava Filter Tilt Associated with Challenging Retrieval
Kostiuk V, Grubman S, Brahmandam A, Schneider E, Tonnessen B, Perez Lozada J, Guzman R, Ochoa Chaar C. The Degree of Inferior Vena Cava Filter Tilt Associated with Challenging Retrieval. Annals Of Vascular Surgery 2024, 109: 135-142. PMID: 39025218, DOI: 10.1016/j.avsg.2024.06.020.Peer-Reviewed Original ResearchIVC filter tiltInferior vena cavaInferior vena cava filter retrievalFilter tiltEndovascular techniquesFilter retrievalInferior vena cava axisRight jugular vein accessInferior vena cava diameterElectronic charts of patientsInferior vena cava filter removalAssociated with technical difficultiesCharts of patientsFailed retrievalJugular vein accessLowest renal veinRight jugular veinRegression analysisFilter placementIVC filtersRenal veinVein accessVena cavaProcedural characteristicsFilter removalPresentation and patterns of reinterventions after revascularization in patients with premature peripheral arterial disease
Sivakumar A, Satam K, Wu Z, Alameddine D, Aboian E, Chaer R, Schermerhorn M, Moreira C, Guzman R, Ochoa Chaar C. Presentation and patterns of reinterventions after revascularization in patients with premature peripheral arterial disease. Journal Of Vascular Surgery 2024, 80: 1776-1785.e1. PMID: 39002606, DOI: 10.1016/j.jvs.2024.07.021.Peer-Reviewed Original ResearchPremature peripheral arterial diseaseLower extremity revascularizationOlder patientsPeripheral arterial diseaseArtery diseaseRetrospective review of consecutive patientsReview of consecutive patientsDistressed Communities IndexAge of presentationFrequency of reinterventionsEnd-stage renal diseaseKaplan-Meier curvesOutcomes of lower extremity revascularizationLong-term outcomesCoronary artery diseaseMALE-free survivalAdverse limb eventsOverall survivalReintervention rateConsecutive patientsFrequent reinterventionsPerioperative complicationsRetrospective reviewNo significant differenceInstitutional experienceThe radiographic relationship of the femoral head, inguinal ligament, and common femoral artery bifurcation for optimal vascular access
Brahmandam A, Huttler J, Bellamkonda K, Setia O, Cardella J, Stewart W, Guzman R, Ochoa Chaar C. The radiographic relationship of the femoral head, inguinal ligament, and common femoral artery bifurcation for optimal vascular access. Journal Of Vascular Surgery 2024, 79: a17-a18. DOI: 10.1016/j.jvs.2024.04.032.Peer-Reviewed Original ResearchIntravascular Ultrasound Use is Associated with Improved Patency in Lower Extremity Peripheral Arterial Interventions
Brahmandam A, Kim T, Parziale S, Deng Y, Setia O, Tonnessen B, Ochoa Chaar C, Guzman R, Aboian E. Intravascular Ultrasound Use is Associated with Improved Patency in Lower Extremity Peripheral Arterial Interventions. Annals Of Vascular Surgery 2024, 106: 410-418. PMID: 38810722, DOI: 10.1016/j.avsg.2024.03.008.Peer-Reviewed Original ResearchChronic limb-threatening ischemiaChronic limb threatening ischemia patientsGeneralized estimating equationsPeripheral vascular interventionsPeripheral arterial diseaseAssociated with improved patencyPredictors of 1-year outcomeIntravascular ultrasound useVascular Quality InitiativeSubgroup analysisAdjunctive useD lesionsTASC CPropensity matchingTreatment modalitiesTrans-Atlantic Inter-Society Consensus (TASC) classificationMajor amputationLimb-threatening ischemiaBalloon angioplastyIntravascular ultrasoundImproved patencyUltrasound useOne-year followQuality InitiativePredictors of patencyAnticoagulation in Patients with Premature Peripheral Artery Disease Undergoing Lower Extremity Revascularization
Kim T, DeWan A, Murray M, Wang H, Mani A, Mena-Hurtado C, Guzman R, Ochoa Chaar C. Anticoagulation in Patients with Premature Peripheral Artery Disease Undergoing Lower Extremity Revascularization. Annals Of Vascular Surgery 2024, 105: 150-157. PMID: 38593922, DOI: 10.1016/j.avsg.2024.02.006.Peer-Reviewed Original ResearchPremature peripheral arterial diseaseAntiplatelet therapyVascular Quality InitiativeArtery diseaseAdjunct to antiplatelet therapyReturn to the operating roomPost-operative anticoagulationCompared to patientsPostoperative antiplatelet therapyOne-year outcomesCongestive heart failureLower extremity revascularizationMajor adverse limb eventsCoronary artery diseaseEffects of anticoagulantsAmputation-free survivalEarly onset of diseaseAdverse limb eventsPeripheral vascular interventionsOnset of diseasePeripheral arterial diseaseLower-extremity revascularizationPropensity score matchingPerioperative mortalityBaseline characteristics
2023
The Utilization of Protamine during Peripheral Vascular Interventions in the VQI
Ali S, Shebl F, Aboian E, Strosberg D, Fischer U, Cardella J, Guzman R, Ochoa Chaar C. The Utilization of Protamine during Peripheral Vascular Interventions in the VQI. Annals Of Vascular Surgery 2023, 101: 72-79. PMID: 38110083, DOI: 10.1016/j.avsg.2023.10.019.Peer-Reviewed Original ResearchPeripheral vascular interventionsAdjusted rate ratiosProtamine useCardiac complicationsPropensity matchingVascular interventionsChronic obstructive pulmonary diseasePropensity scoreCharacteristics of patientsPeripheral arterial diseaseCongestive heart failureObstructive pulmonary diseaseMultivariable Poisson regressionUse of protamineSignificant differencesMedical comorbiditiesP2Y12 inhibitorsPerioperative bleedingPerioperative medicationsPerioperative outcomesDistal embolizationPatient comorbiditiesCarotid surgeryHeart failurePulmonary diseaseThe development of a novel endovascular grasper for challenging inferior vena cava filter retrieval
Chaar C, Kostiuk V, Rodriguez P, Kim T, Rathbone D, Ghandour L, Burns R, Thorn S, Sinusas A, Guzman R, Dardik A. The development of a novel endovascular grasper for challenging inferior vena cava filter retrieval. Journal Of Vascular Surgery Venous And Lymphatic Disorders 2023, 12: 101731. PMID: 38081514, PMCID: PMC11523361, DOI: 10.1016/j.jvsv.2023.101731.Peer-Reviewed Original ResearchSystematic review and meta-analysis of the genetics of peripheral arterial disease
Ochoa Chaar C, Kim T, Alameddine D, DeWan A, Guzman R, Dardik A, Grossetta Nardini H, Wallach J, Kullo I, Murray M. Systematic review and meta-analysis of the genetics of peripheral arterial disease. JVS Vascular Science 2023, 5: 100133. PMID: 38314202, PMCID: PMC10832467, DOI: 10.1016/j.jvssci.2023.100133.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsGenome-wide association studiesDNA variantsWide association studyRecent genome-wide association studiesSmall candidate gene studiesCandidate gene studiesGWAS studiesCandidate genesAssociation studiesGene studiesGenetic researchGeneticsOnly variantVariantsHepatic lipaseGenesProgressionSignificant variation
2020
Comparison of Atherectomy to Balloon Angioplasty and Stenting for Isolated Femoropopliteal Revascularization
Bai H, Fereydooni A, Zhuo H, Zhang Y, Tonnessen B, Guzman RJ, Ochoa Chaar CI. Comparison of Atherectomy to Balloon Angioplasty and Stenting for Isolated Femoropopliteal Revascularization. Annals Of Vascular Surgery 2020, 69: 261-273. PMID: 32512112, DOI: 10.1016/j.avsg.2020.05.019.Peer-Reviewed Original ResearchConceptsPercutaneous transluminal angioplastyMajor ipsilateral amputationIpsilateral amputationPrimary patencyDistal embolizationFemoropopliteal diseaseBalloon angioplastyTechnical successStatus improvementAnkle-brachial index improvementSignificant additional clinical benefitSociety Consensus (TASC) II classificationChronic obstructive pulmonary diseaseConcomitant open surgeryLower ratesOutcomes of atherectomyUse of atherectomyAcute limb ischemiaOne-year outcomesVascular Quality InitiativeCongestive heart failureHigher reintervention rateLower extremity revascularizationObstructive pulmonary diseaseAdditional clinical benefitTrends of hospital-based surgery for varicose veins in the elderly
Kim TI, Zhang Y, Guzman RJ, Ochoa Chaar CI. Trends of hospital-based surgery for varicose veins in the elderly. Journal Of Vascular Surgery Venous And Lymphatic Disorders 2020, 9: 146-153.e2. PMID: 32360785, DOI: 10.1016/j.jvsv.2020.04.016.Peer-Reviewed Original ResearchMeSH KeywordsAblation TechniquesAge FactorsAgedAged, 80 and overAnesthesia, GeneralDatabases, FactualFemaleHospitalizationHumansMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesVaricose VeinsVascular Surgical ProceduresVenous InsufficiencyConceptsProportion of patientsAdverse eventsVenous ablationGeneral anesthesiaVaricose veinsAge groupsVein ablationVein surgeryHospital-based surgeryCurrent Procedural Terminology codesHigh-risk patientsVaricose vein surgeryProcedural Terminology codesLarge national databaseYounger age groupsPaucity of dataMore comorbiditiesAnesthesiologists classificationOverall morbidityVenous surgeryDialysis populationVenous insufficiencyOpen surgeryConservative measuresOperative characteristics
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