2024
The “mini-extended” nasoseptal flap for reconstruction of sella to planum skull base defects
Rimmer R, Manes R, Omay S. The “mini-extended” nasoseptal flap for reconstruction of sella to planum skull base defects. American Journal Of Otolaryngology 2024, 45: 104437. PMID: 39102763, DOI: 10.1016/j.amjoto.2024.104437.Peer-Reviewed Original ResearchTaste dysfunction after endoscopic endonasal resection of olfactory groove meningioma: Case series and review of the literature
Fecker A, Studer M, Manes R, Omay S, Detwiller K, Smith T, Andersen P, Sanusi O, Collins K, Geltzeiler M, Rimmer R. Taste dysfunction after endoscopic endonasal resection of olfactory groove meningioma: Case series and review of the literature. American Journal Of Otolaryngology 2024, 45: 104302. PMID: 38678798, DOI: 10.1016/j.amjoto.2024.104302.Peer-Reviewed Original ResearchResection of olfactory groove meningiomasOlfactory groove meningiomasEndoscopic endonasal resectionMinority of patientsSense of tasteTaste changesSeverity of symptomsOlfactory dysfunctionTaste dysfunctionMedian timeCase seriesClinical characteristicsOlfactory functionPatient counselingPatientsSense of smellAssociated with lateralizationResectionMeningiomasSurgeryDysfunctionRated severityNeoplasmsSurvey responsesAgeusiaAssociation of CT-based Lobar Contusion Volumes and Locations with Post-traumatic Epilepsy (P5-1.003)
Shrishail N, Wheelock J, Sanders W, Doherty D, Kim J, Schlecter M, Sivaraju A, Hirsch L, Omay S, Sheth K, Gilmore E, Edlow B, Kim J. Association of CT-based Lobar Contusion Volumes and Locations with Post-traumatic Epilepsy (P5-1.003). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000206260.Peer-Reviewed Original ResearchLow-field, Portable Magnetic Resonance Imaging to Assess Hematoma Volume in Traumatic Brain Injury Patients (P10-5.008)
Zabinska J, Yadlapalli V, Mazurek M, Parasuram N, Lalwani D, Peasley E, Gilmore E, Kim J, Omay S, Sze G, Payabvash S, Sorby-Adams A, Iglesias J, Rosen M, Kimberly W, Sheth K. Low-field, Portable Magnetic Resonance Imaging to Assess Hematoma Volume in Traumatic Brain Injury Patients (P10-5.008). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000208210.Peer-Reviewed Original Research
2023
A PILOT STUDY: SPATIOTEMPORALLY-RESOLVED MOLECULAR MECHANISMS OF ACUTE IMMUNE AND NEUROMODULATORY RESPONSES TO TRAUMATIC BRAIN INJURY
Mohammed F, Mcguone D, Omay S, Omay Z, Zhou J. A PILOT STUDY: SPATIOTEMPORALLY-RESOLVED MOLECULAR MECHANISMS OF ACUTE IMMUNE AND NEUROMODULATORY RESPONSES TO TRAUMATIC BRAIN INJURY. IBRO Neuroscience Reports 2023, 15: s189-s190. DOI: 10.1016/j.ibneur.2023.08.289.Peer-Reviewed Original ResearchSporadic pituitary adenoma with somatic double-hit loss of MEN1
Hong C, Alanya H, DiStasio M, Boulware S, Rimmer R, Omay S, Erson-Omay E. Sporadic pituitary adenoma with somatic double-hit loss of MEN1. Pituitary 2023, 26: 488-494. PMID: 37438451, DOI: 10.1007/s11102-023-01336-1.Peer-Reviewed Original ResearchPortable MRI to assess optic chiasm decompression after endoscopic endonasal resection of sellar and suprasellar lesions.
Hong C, Lamsam L, Yadlapalli V, Parasuram N, Mazurek M, Chavva I, Lalwani D, Zabinska J, Schiff S, Manes R, Vining E, Rimmer R, Kimberly W, Sheth K, Omay S. Portable MRI to assess optic chiasm decompression after endoscopic endonasal resection of sellar and suprasellar lesions. Journal Of Neurosurgery 2023, 139: 1664-1670. PMID: 37347618, DOI: 10.3171/2023.5.jns23174.Peer-Reviewed Original ResearchConceptsEndoscopic endonasal surgeryOptic nerve decompressionEndonasal surgerySuprasellar lesionsNerve decompressionOptic chiasmThird ventricleConventional MRIOptic chiasm compressionEndoscopic endonasal resectionChiasm compressionPreoperative imagingSingle institutionEndonasal resectionMRI availabilityRoutine MRISignificant interrater reliabilitySuprasellar pathologiesSurgeryNeurosurgical oncologyLinear mixed-effects modelsPortable MRIPatientsMRIMixed-effects modelsClinical and genomic differences in supratentorial versus infratentorial NF2 mutant meningiomas.
Tabor J, O'Brien J, Vasandani S, Vetsa S, Lei H, Jalal M, Marianayagam N, Jin L, Millares Chavez M, Haynes J, Dincer A, Yalcin K, Aguilera S, Omay S, Mishra-Gorur K, McGuone D, Morales-Valero S, Fulbright R, Gunel M, Erson-Omay E, Moliterno J. Clinical and genomic differences in supratentorial versus infratentorial NF2 mutant meningiomas. Journal Of Neurosurgery 2023, 139: 1648-1656. PMID: 37243548, DOI: 10.3171/2023.4.jns222929.Peer-Reviewed Original ResearchConceptsSubtotal resectionSupratentorial tumorsElevated Ki-67High-risk featuresProgression-free survivalChromosome 1p deletionInfratentorial counterpartsInfratentorial tumorsPostoperative managementSomatic driver mutationsCerebral convexityGrade IIInfratentorial meningiomasKi-67Posterior fossaLoss of heterozygosityMeningiomasResectionTumorsWhole-exome sequencing dataDriver mutationsHigh gradeSignificant differencesExome sequencing dataSporadic meningiomasImaging metabolism of deuterated glucose in patients with primary brain tumors
Corbin Z, Liu Y, Fulbright R, Thaw-Poon S, Baehring J, Blondin N, Kim P, Omuro A, Chiang V, Moliterno J, Omay S, Piepmeier J, Rothman D, de Graaf R, De Feyter H. Imaging metabolism of deuterated glucose in patients with primary brain tumors. Proceedings Of The International Society For Magnetic Resonance In Medicine ... Scientific Meeting And Exhibition. 2023 DOI: 10.58530/2023/0142.Peer-Reviewed Original Research3D printing for virtual surgical planning of nasoseptal flap skull‐base reconstruction: A proof‐of‐concept study
Kayastha D, Wiznia D, Manes R, Omay S, Khoury T, Rimmer R. 3D printing for virtual surgical planning of nasoseptal flap skull‐base reconstruction: A proof‐of‐concept study. International Forum Of Allergy & Rhinology 2023, 13: 2073-2075. PMID: 37026426, DOI: 10.1002/alr.23165.Peer-Reviewed Original ResearchSubdural empyema secondary to pansinusitis after coronavirus disease 2019 infection in an immunocompetent patient: illustrative case
Hong C, Prust M, Manes R, Rimmer R, Omay S. Subdural empyema secondary to pansinusitis after coronavirus disease 2019 infection in an immunocompetent patient: illustrative case. Journal Of Neurosurgery Case Lessons 2023, 5: case22525. PMID: 36806010, PMCID: PMC10550626, DOI: 10.3171/case22525.Peer-Reviewed Original ResearchIntracranial infectionSubdural empyemaAntimicrobial therapyCoronavirus disease 2019 (COVID-19) infectionPolymerase chain reaction testingMultidisciplinary surgical managementRapid clinical improvementAggressive surgical approachDisease 2019 infectionFull clinical recoveryTime of presentationCoronavirus disease 2019COVID-19Clinical improvementClinical recoveryImmunocompetent patientsImmunocompetent maleSurgical managementSignificant complicationsSurgical approachDisease 2019Negative culturesPositive culturesHealthy individualsReaction testingPrimary hypothyroidism presenting as neuropsychiatric symptoms and pituitary enlargement in a young woman: illustrative case
Haider S, Templeton K, Omay S, Inzucchi S. Primary hypothyroidism presenting as neuropsychiatric symptoms and pituitary enlargement in a young woman: illustrative case. Journal Of Neurosurgery Case Lessons 2023, 5: case22496. PMID: 36794728, PMCID: PMC10550602, DOI: 10.3171/case22496.Peer-Reviewed Original ResearchPituitary enlargementPrimary hypothyroidismPituitary hyperplasiaElevated thyroid-stimulating hormoneSevere primary hypothyroidismThyroid-stimulating hormoneComputed tomography scanMagnetic resonance imagingLevothyroxine replacementHormone replacementNeuropsychiatric symptomsRare presentationSellar massSurgical interventionTomography scanCommon causePituitary adenomasPhysiological causesResonance imagingPsychiatry departmentYoung womenHypothyroidismHyperplasiaSymptomsEnlargementVariables of Pituitary Adenoma Recurrence/Regrowth
Hilton B, Adeyina O, Yalcin K, Hong C, Erson-Omay Z, Omay S. Variables of Pituitary Adenoma Recurrence/Regrowth. Journal Of Neurological Surgery Part B Skull Base 2023, 84: s1-s344. DOI: 10.1055/s-0043-1762395.Peer-Reviewed Original ResearchThe Impact of Genomic Characterization for Pituitary Adenoma Classification
Yalcin K, Hilton B, Adeyina O, Hong C, Omay S, Erson-Omay Z. The Impact of Genomic Characterization for Pituitary Adenoma Classification. Journal Of Neurological Surgery Part B Skull Base 2023, 84: s1-s344. DOI: 10.1055/s-0043-1762405.Peer-Reviewed Original ResearchPortable MRI to Assess Optic Nerve Decompression after Endoscopic Endonasal Resection of Sellar Lesions
Hong C, Lamsam L, Crawford A, Sheth K, Rimmer R, Omay S. Portable MRI to Assess Optic Nerve Decompression after Endoscopic Endonasal Resection of Sellar Lesions. Journal Of Neurological Surgery Part B Skull Base 2023, 84: s1-s344. DOI: 10.1055/s-0043-1762183.Peer-Reviewed Original ResearchFuture of Neurology & Technology: Neuroimaging Made Accessible Using Low-Field, Portable MRI
Parasuram N, Crawford A, Mazurek M, Chavva I, Beekman R, Gilmore E, Petersen N, Payabvash S, Sze G, Eugenio Iglesias J, Omay S, Matouk C, Longbrake E, de Havenon A, Schiff S, Rosen M, Kimberly W, Sheth K. Future of Neurology & Technology: Neuroimaging Made Accessible Using Low-Field, Portable MRI. Neurology 2023, 100: 1067-1071. PMID: 36720639, PMCID: PMC10259275, DOI: 10.1212/wnl.0000000000207074.Peer-Reviewed Original Research
2022
Pituitary Apoplexy
Hong C, Omay S. Pituitary Apoplexy. New England Journal Of Medicine 2022, 387: 2366-2366. PMID: 36547664, DOI: 10.1056/nejmicm2204942.Peer-Reviewed Original ResearchNanoparticle-based drug delivery for the treatment of traumatic brain injury
Mohammed F, Omay S, Sheth K, Zhou J. Nanoparticle-based drug delivery for the treatment of traumatic brain injury. Expert Opinion On Drug Delivery 2022, 20: 55-73. PMID: 36420918, PMCID: PMC9983310, DOI: 10.1080/17425247.2023.2152001.Peer-Reviewed Original ResearchConceptsTraumatic brain injuryBrain injurySecondary outcomesClinical trialsPathophysiology of TBIPhase III clinical trialsPhase II clinical trialClinical management strategiesSite of injuryOff-target toxicityPharmacological treatmentBrain penetrationLow off-target toxicityExperimental animalsInjuryChronic timescalesDosage thresholdDrug deliveryTrialsDrug targetingOutcomesTreatmentDeliveryPathophysiologyQuantitative epileptiform burden and electroencephalography background features predict post-traumatic epilepsy
Chen Y, Li S, Ge W, Jing J, Chen HY, Doherty D, Herman A, Kaleem S, Ding K, Osman G, Swisher CB, Smith C, Maciel CB, Alkhachroum A, Lee JW, Dhakar MB, Gilmore EJ, Sivaraju A, Hirsch LJ, Omay SB, Blumenfeld H, Sheth KN, Struck AF, Edlow BL, Westover MB, Kim JA. Quantitative epileptiform burden and electroencephalography background features predict post-traumatic epilepsy. Journal Of Neurology Neurosurgery & Psychiatry 2022, 94: 245-249. PMID: 36241423, PMCID: PMC9931627, DOI: 10.1136/jnnp-2022-329542.Peer-Reviewed Original ResearchConceptsPost-traumatic epilepsyTraumatic brain injuryCT abnormalitiesElectroencephalography featuresAdmission Glasgow Coma Scale scoreGlasgow Coma Scale scoreRetrospective case-control studyMultivariable logistic regression analysisRisk stratification modelCase-control studyLogistic regression analysisTBI admissionsSevere complicationsFuture trialsBrain injuryCT reportsSeizure diagnosisPredictive valueScale scorePatientsLogistic regressionStratification modelQuantitative electroencephalogramTBI mechanismsRegression analysisMinimally-Invasive Resection of a Racemose Neurocysticercal Cyst.
Trubin PA, Omay SB, Ko AI. Minimally-Invasive Resection of a Racemose Neurocysticercal Cyst. American Journal Of Tropical Medicine And Hygiene 2022, 107: 4-5. PMID: 35605635, PMCID: PMC9294708, DOI: 10.4269/ajtmh.22-0100.Peer-Reviewed Original Research